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The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity.
Stienstra R, Joosten LA, Koenen T, van Tits B, van Diepen JA, van den Berg SA, Rensen PC, Voshol PJ, Fantuzzi G, Hijmans A, Kersten S, Müller M, van den Berg WB, van Rooijen N, Wabitsch M, Kullberg BJ, van der Meer JW, Kanneganti T, Tack CJ, Netea MG. Stienstra R, et al. Cell Metab. 2010 Dec 1;12(6):593-605. doi: 10.1016/j.cmet.2010.11.011. Cell Metab. 2010. PMID: 21109192 Free PMC article.
Inflammasome is a central player in the induction of obesity and insulin resistance.
Stienstra R, van Diepen JA, Tack CJ, Zaki MH, van de Veerdonk FL, Perera D, Neale GA, Hooiveld GJ, Hijmans A, Vroegrijk I, van den Berg S, Romijn J, Rensen PC, Joosten LA, Netea MG, Kanneganti TD. Stienstra R, et al. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15324-9. doi: 10.1073/pnas.1100255108. Epub 2011 Aug 29. Proc Natl Acad Sci U S A. 2011. PMID: 21876127 Free PMC article.
PPAR-alpha dependent regulation of vanin-1 mediates hepatic lipid metabolism.
van Diepen JA, Jansen PA, Ballak DB, Hijmans A, Hooiveld GJ, Rommelaere S, Galland F, Naquet P, Rutjes FP, Mensink RP, Schrauwen P, Tack CJ, Netea MG, Kersten S, Schalkwijk J, Stienstra R. van Diepen JA, et al. J Hepatol. 2014 Aug;61(2):366-72. doi: 10.1016/j.jhep.2014.04.013. Epub 2014 Apr 18. J Hepatol. 2014. PMID: 24751833
IL-37 protects against obesity-induced inflammation and insulin resistance.
Ballak DB, van Diepen JA, Moschen AR, Jansen HJ, Hijmans A, Groenhof GJ, Leenders F, Bufler P, Boekschoten MV, Müller M, Kersten S, Li S, Kim S, Eini H, Lewis EC, Joosten LA, Tilg H, Netea MG, Tack CJ, Dinarello CA, Stienstra R. Ballak DB, et al. Nat Commun. 2014 Sep 3;5:4711. doi: 10.1038/ncomms5711. Nat Commun. 2014. PMID: 25182023 Free article.
Corrigendum: IL-37 protects against obesity-induced inflammation and insulin resistance.
Ballak DB, van Diepen JA, Moschen AR, Jansen HJ, Hijmans A, Groenhof GJ, Leenders F, Bufler P, Boekschoten MV, Müller M, Kersten S, Li S, Kim S, Eini H, Lewis EC, Joosten LA, Tilg H, Netea MG, Tack CJ, Dinarello CA, Stienstra R. Ballak DB, et al. Nat Commun. 2015 Jan 12;6:6039. doi: 10.1038/ncomms7039. Nat Commun. 2015. PMID: 25580956 Free article. No abstract available.
43 results