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Lipid Tales: Optimizing Arylomycin Membrane Anchors.
Koehler MFT, Chen YC, Chen Y, Chen Y, Crawford JJ, Durk MR, Garland K, Hanan EJ, Higuchi RI, Hu H, Ly CQ, Paraselli PG, Roberts TC, Schwarz JB, Smith PA, Yu Z, Heise CE. Koehler MFT, et al. Among authors: higuchi ri. ACS Med Chem Lett. 2023 Oct 11;14(11):1524-1530. doi: 10.1021/acsmedchemlett.3c00327. eCollection 2023 Nov 9. ACS Med Chem Lett. 2023. PMID: 37974942
Optimized arylomycins are a new class of Gram-negative antibiotics.
Smith PA, Koehler MFT, Girgis HS, Yan D, Chen Y, Chen Y, Crawford JJ, Durk MR, Higuchi RI, Kang J, Murray J, Paraselli P, Park S, Phung W, Quinn JG, Roberts TC, Rougé L, Schwarz JB, Skippington E, Wai J, Xu M, Yu Z, Zhang H, Tan MW, Heise CE. Smith PA, et al. Among authors: higuchi ri. Nature. 2018 Sep;561(7722):189-194. doi: 10.1038/s41586-018-0483-6. Epub 2018 Sep 12. Nature. 2018. PMID: 30209367
Synthesis and characterization of nonsteroidal glucocorticoid receptor modulators for multiple myeloma.
Hudson AR, Roach SL, Higuchi RI, Phillips DP, Bissonnette RP, Lamph WW, Yen J, Li Y, Adams ME, Valdez LJ, Vassar A, Cuervo C, Kallel EA, Gharbaoui CJ, Mais DE, Miner JN, Marschke KB, Rungta D, Negro-Vilar A, Zhi L. Hudson AR, et al. Among authors: higuchi ri. J Med Chem. 2007 Sep 20;50(19):4699-709. doi: 10.1021/jm070370z. Epub 2007 Aug 17. J Med Chem. 2007. PMID: 17705362
5(Z)-benzylidene-1,2-dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5H-1-aza-6-oxa-chrysenes as non-steroidal glucocorticoid receptor modulators.
Ardecky RJ, Hudson AR, Phillips DP, Tyhonas JS, Deckhut C, Lau TL, Li Y, Martinborough EA, Roach SL, Higuchi RI, Lopez FJ, Marschke KB, Miner JN, Karanewsky DS, Negro-Vilar A, Zhi L. Ardecky RJ, et al. Among authors: higuchi ri. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4158-62. doi: 10.1016/j.bmcl.2007.05.062. Epub 2007 May 23. Bioorg Med Chem Lett. 2007. PMID: 17553679
19 results