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Reactive oxygen species upregulate expression of muscle atrophy-associated ubiquitin ligase Cbl-b in rat L6 skeletal muscle cells.
Uchida T, Sakashita Y, Kitahata K, Yamashita Y, Tomida C, Kimori Y, Komatsu A, Hirasaka K, Ohno A, Nakao R, Higashitani A, Higashibata A, Ishioka N, Shimazu T, Kobayashi T, Okumura Y, Choi I, Oarada M, Mills EM, Teshima-Kondo S, Takeda S, Tanaka E, Tanaka K, Sokabe M, Nikawa T. Uchida T, et al. Among authors: higashitani a. Am J Physiol Cell Physiol. 2018 Jun 1;314(6):C721-C731. doi: 10.1152/ajpcell.00184.2017. Epub 2018 Mar 7. Am J Physiol Cell Physiol. 2018. PMID: 29513566 Free article.
Ultra-high-purity iron is a novel and very compatible biomaterial.
Khan L, Sato K, Okuyama S, Kobayashi T, Ohashi K, Hirasaka K, Nikawa T, Takada K, Higashitani A, Abiko K. Khan L, et al. Among authors: higashitani a. J Mech Behav Biomed Mater. 2020 Jun;106:103744. doi: 10.1016/j.jmbbm.2020.103744. Epub 2020 Mar 27. J Mech Behav Biomed Mater. 2020. PMID: 32250954 Free article.
Findings from recent studies by the Japan Aerospace Exploration Agency examining musculoskeletal atrophy in space and on Earth.
Furukawa S, Chatani M, Higashitani A, Higashibata A, Kawano F, Nikawa T, Numaga-Tomita T, Ogura T, Sato F, Sehara-Fujisawa A, Shinohara M, Shimazu T, Takahashi S, Watanabe-Takano H. Furukawa S, et al. Among authors: higashitani a. NPJ Microgravity. 2021 May 26;7(1):18. doi: 10.1038/s41526-021-00145-9. NPJ Microgravity. 2021. PMID: 34039989 Free PMC article. Review.
Mitochondrial dysfunction causes Ca2+ overload and ECM degradation-mediated muscle damage in C. elegans.
Sudevan S, Takiura M, Kubota Y, Higashitani N, Cooke M, Ellwood RA, Etheridge T, Szewczyk NJ, Higashitani A. Sudevan S, et al. Among authors: higashitani a, higashitani n. FASEB J. 2019 Aug;33(8):9540-9550. doi: 10.1096/fj.201802298R. Epub 2019 Jun 4. FASEB J. 2019. PMID: 31162948 Free PMC article.
In conclusion, we have established ECM degradation as an important pathway of muscle damage.-Sudevan, S., Takiura, M., Kubota, Y., Higashitani, N., Cooke, M., Ellwood, R. A., Etheridge, T., Szewczyk, N. J., Higashitani, A. Mitochondrial dysfunction cau …
In conclusion, we have established ECM degradation as an important pathway of muscle damage.-Sudevan, S., Takiura, M., Kubota, Y., Higash
125 results