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Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity.
Paukštytė J, López Cabezas RM, Feng Y, Tong K, Schnyder D, Elomaa E, Gregorova P, Doudin M, Särkkä M, Sarameri J, Lippi A, Vihinen H, Juutila J, Nieminen A, Törönen P, Holm L, Jokitalo E, Krisko A, Huiskonen J, Sarin LP, Hietakangas V, Picotti P, Barral Y, Saarikangas J. Paukštytė J, et al. Among authors: hietakangas v. Mol Cell. 2023 Sep 21;83(18):3360-3376.e11. doi: 10.1016/j.molcel.2023.08.015. Epub 2023 Sep 11. Mol Cell. 2023. PMID: 37699397 Free article.
Metabolic gene regulation by Drosophila GATA transcription factor Grain.
Kokki K, Lamichane N, Nieminen AI, Ruhanen H, Morikka J, Robciuc M, Rovenko BM, Havula E, Käkelä R, Hietakangas V. Kokki K, et al. Among authors: hietakangas v. PLoS Genet. 2021 Oct 11;17(10):e1009855. doi: 10.1371/journal.pgen.1009855. eCollection 2021 Oct. PLoS Genet. 2021. PMID: 34634038 Free PMC article.
Metabolic determination of cell fate through selective inheritance of mitochondria.
Döhla J, Kuuluvainen E, Gebert N, Amaral A, Englund JI, Gopalakrishnan S, Konovalova S, Nieminen AI, Salminen ES, Torregrosa Muñumer R, Ahlqvist K, Yang Y, Bui H, Otonkoski T, Käkelä R, Hietakangas V, Tyynismaa H, Ori A, Katajisto P. Döhla J, et al. Among authors: hietakangas v. Nat Cell Biol. 2022 Feb;24(2):148-154. doi: 10.1038/s41556-021-00837-0. Epub 2022 Feb 14. Nat Cell Biol. 2022. PMID: 35165416 Free PMC article.
Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.
Balboa D, Barsby T, Lithovius V, Saarimäki-Vire J, Omar-Hmeadi M, Dyachok O, Montaser H, Lund PE, Yang M, Ibrahim H, Näätänen A, Chandra V, Vihinen H, Jokitalo E, Kvist J, Ustinov J, Nieminen AI, Kuuluvainen E, Hietakangas V, Katajisto P, Lau J, Carlsson PO, Barg S, Tengholm A, Otonkoski T. Balboa D, et al. Among authors: hietakangas v. Nat Biotechnol. 2022 Jul;40(7):1042-1055. doi: 10.1038/s41587-022-01219-z. Epub 2022 Mar 3. Nat Biotechnol. 2022. PMID: 35241836 Free PMC article.
Sugar-responsive inhibition of Myc-dependent ribosome biogenesis by Clockwork orange.
van den Berg L, Kokki K, Wowro SJ, Petricek KM, Deniz O, Stegmann CA, Robciuc M, Teesalu M, Melvin RG, Nieminen AI, Schupp M, Hietakangas V. van den Berg L, et al. Among authors: hietakangas v. Cell Rep. 2023 Jul 25;42(7):112739. doi: 10.1016/j.celrep.2023.112739. Epub 2023 Jul 4. Cell Rep. 2023. PMID: 37405919 Free article.
55 results