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γ-Secretase directly sheds the survival receptor BCMA from plasma cells.
Laurent SA, Hoffmann FS, Kuhn PH, Cheng Q, Chu Y, Schmidt-Supprian M, Hauck SM, Schuh E, Krumbholz M, Rübsamen H, Wanngren J, Khademi M, Olsson T, Alexander T, Hiepe F, Pfister HW, Weber F, Jenne D, Wekerle H, Hohlfeld R, Lichtenthaler SF, Meinl E. Laurent SA, et al. Among authors: hiepe f. Nat Commun. 2015 Jun 11;6:7333. doi: 10.1038/ncomms8333. Nat Commun. 2015. PMID: 26065893 Free PMC article.
Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system.
Alexander T, Thiel A, Rosen O, Massenkeil G, Sattler A, Kohler S, Mei H, Radtke H, Gromnica-Ihle E, Burmester GR, Arnold R, Radbruch A, Hiepe F. Alexander T, et al. Among authors: hiepe f. Blood. 2009 Jan 1;113(1):214-23. doi: 10.1182/blood-2008-07-168286. Epub 2008 Sep 29. Blood. 2009. PMID: 18824594 Free article. Clinical Trial.
Development and resolution of secondary autoimmunity after autologous haematopoietic stem cell transplantation for systemic lupus erythematosus: competition of plasma cells for survival niches?
Alexander T, Schneider S, Hoyer B, Cheng Q, Thiel A, Ziemer S, Burmester GR, Arnold R, Radbruch A, Hiepe F. Alexander T, et al. Among authors: hiepe f. Ann Rheum Dis. 2013 Jun;72(6):1102-4. doi: 10.1136/annrheumdis-2012-202729. Epub 2013 Jan 29. Ann Rheum Dis. 2013. PMID: 23361083 No abstract available.
309 results