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Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization.
Romano LEL, Aw WY, Hixson KM, Novoselova TV, Havener TM, Howell S, Taylor-Blake B, Hall CL, Xing L, Beri J, Nethisinghe S, Perna L, Hatimy A, Altadonna GC, Graves LM, Herring LE, Hickey AJ, Thalassinos K, Chapple JP, Wolter JM. Romano LEL, et al. Among authors: hickey aj. Cell Rep. 2022 Nov 1;41(5):111580. doi: 10.1016/j.celrep.2022.111580. Cell Rep. 2022. PMID: 36323248 Free PMC article.
Microphysiological model of PIK3CA-driven vascular malformations reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation.
Aw WY, Cho C, Wang H, Cooper AH, Doherty EL, Rocco D, Huang SA, Kubik S, Whitworth CP, Armstrong R, Hickey AJ, Griffith B, Kutys ML, Blatt J, Polacheck WJ. Aw WY, et al. Among authors: hickey aj. Sci Adv. 2023 Feb 15;9(7):eade8939. doi: 10.1126/sciadv.ade8939. Epub 2023 Feb 15. Sci Adv. 2023. PMID: 36791204 Free PMC article.
Pharmacokinetic Considerations for Optimizing Inhaled Spray-Dried Pyrazinoic Acid Formulations.
Yeshwante SB, Hanafin P, Miller BK, Rank L, Murcia S, Xander C, Annis A, Baxter VK, Anderson EJ, Jermain B, Konicki R, Schmalstig AA, Stewart I, Braunstein M, Hickey AJ, Rao GG. Yeshwante SB, et al. Among authors: hickey aj. Mol Pharm. 2023 Sep 4;20(9):4491-4504. doi: 10.1021/acs.molpharmaceut.3c00199. Epub 2023 Aug 17. Mol Pharm. 2023. PMID: 37590399
Inhaled "Muco-Trapping" Monoclonal Antibody Effectively Treats Established Respiratory Syncytial Virus (RSV) Infections.
McSweeney MD, Alnajjar S, Schaefer AM, Richardson Z, Wolf W, Stewart I, Sriboonyapirat P, McCallen J, Farmer E, Nzati B, Lord S, Farrer B, Moench TR, Kumar PA, Arora H, Pickles RJ, Hickey AJ, Ackermann M, Lai SK. McSweeney MD, et al. Among authors: hickey aj. Adv Sci (Weinh). 2024 Mar;11(12):e2306729. doi: 10.1002/advs.202306729. Epub 2024 Jan 15. Adv Sci (Weinh). 2024. PMID: 38225749 Free PMC article.
Quasi-2D Fermi surface in the anomalous superconductor UTe2.
Eaton AG, Weinberger TI, Popiel NJM, Wu Z, Hickey AJ, Cabala A, Pospíšil J, Prokleška J, Haidamak T, Bastien G, Opletal P, Sakai H, Haga Y, Nowell R, Benjamin SM, Sechovský V, Lonzarich GG, Grosche FM, Vališka M. Eaton AG, et al. Among authors: hickey aj. Nat Commun. 2024 Jan 3;15(1):223. doi: 10.1038/s41467-023-44110-4. Nat Commun. 2024. PMID: 38172154 Free PMC article.
iBCS: 3. A Biopharmaceutics Classification System for Orally Inhaled Drug Products.
Hastedt JE, Bäckman P, Cabal A, Clark A, Ehrhardt C, Forbes B, Hickey AJ, Hochhaus G, Jiang W, Kassinos S, Kuehl PJ, Prime D, Son YJ, Teague S, Tehler U, Wylie J. Hastedt JE, et al. Among authors: hickey aj. Mol Pharm. 2024 Jan 1;21(1):164-172. doi: 10.1021/acs.molpharmaceut.3c00685. Epub 2023 Dec 7. Mol Pharm. 2024. PMID: 38059771 Free PMC article.
310 results