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Human hepatic in vitro models reveal distinct anti-NASH potencies of PPAR agonists.
Boeckmans J, Natale A, Rombaut M, Buyl K, Cami B, De Boe V, Heymans A, Rogiers V, De Kock J, Vanhaecke T, Rodrigues RM. Boeckmans J, et al. Among authors: heymans a. Cell Biol Toxicol. 2021 Apr;37(2):293-311. doi: 10.1007/s10565-020-09544-2. Epub 2020 Jul 1. Cell Biol Toxicol. 2021. PMID: 32613381
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG cell line as a rapid and reliable tool for improved in vitro hazard assessment.
Ates G, Mertens B, Heymans A, Verschaeve L, Milushev D, Vanparys P, Roosens NHC, De Keersmaecker SCJ, Rogiers V, Doktorova TY. Ates G, et al. Among authors: heymans a. Arch Toxicol. 2018 Apr;92(4):1593-1608. doi: 10.1007/s00204-018-2172-5. Epub 2018 Feb 6. Arch Toxicol. 2018. PMID: 29411056
Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model?
Doktorova TY, Yildirimman R, Ceelen L, Vilardell M, Vanhaecke T, Vinken M, Ates G, Heymans A, Gmuender H, Bort R, Corvi R, Phrakonkham P, Li R, Mouchet N, Chesne C, van Delft J, Kleinjans J, Castell J, Herwig R, Rogiers V. Doktorova TY, et al. Among authors: heymans a. EXCLI J. 2014 May 28;13:623-37. eCollection 2014. EXCLI J. 2014. PMID: 26417288 Free PMC article.
In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.
Ates G, Raitano G, Heymans A, Van Bossuyt M, Vanparys P, Mertens B, Chesne C, Roncaglioni A, Milushev D, Benfenati E, Rogiers V, Doktorova TY. Ates G, et al. Among authors: heymans a. Mutagenesis. 2016 Jul;31(4):453-61. doi: 10.1093/mutage/gew008. Epub 2016 Mar 15. Mutagenesis. 2016. PMID: 26980085
18 results