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Structure-Based Design of High-Affinity Macrocyclic FKBP51 Inhibitors.
Bauder M, Meyners C, Purder PL, Merz S, Sugiarto WO, Voll AM, Heymann T, Hausch F. Bauder M, et al. Among authors: heymann t. J Med Chem. 2021 Mar 25;64(6):3320-3349. doi: 10.1021/acs.jmedchem.0c02195. Epub 2021 Mar 5. J Med Chem. 2021. PMID: 33666419
Macrocyclic FKBP51 Ligands Define a Transient Binding Mode with Enhanced Selectivity.
Voll AM, Meyners C, Taubert MC, Bajaj T, Heymann T, Merz S, Charalampidou A, Kolos J, Purder PL, Geiger TM, Wessig P, Gassen NC, Bracher A, Hausch F. Voll AM, et al. Among authors: heymann t. Angew Chem Int Ed Engl. 2021 Jun 7;60(24):13257-13263. doi: 10.1002/anie.202017352. Epub 2021 May 7. Angew Chem Int Ed Engl. 2021. PMID: 33843131 Free PMC article.
SAFit2 reduces neuroinflammation and ameliorates nerve injury-induced neuropathic pain.
Wedel S, Mathoor P, Rauh O, Heymann T, Ciotu CI, Fuhrmann DC, Fischer MJM, Weigert A, de Bruin N, Hausch F, Geisslinger G, Sisignano M. Wedel S, et al. Among authors: heymann t. J Neuroinflammation. 2022 Oct 10;19(1):254. doi: 10.1186/s12974-022-02615-7. J Neuroinflammation. 2022. PMID: 36217203 Free PMC article.
49 results