Heyen J - Search Results

1

CD40 agonist-induced IL-12p40 potentiates hepatotoxicity.

Bonnans C, Thomas G, He W, Jung B, Chen W, Liao M, Heyen J, Buetow B, Pillai S, Matsumoto D, Chaparro-Riggers J, Salek-Ardakani S, Qu Y. Bonnans C, et al. Among authors: heyen j. J Immunother Cancer. 2020 May;8(1):e000624. doi: 10.1136/jitc-2020-000624. J Immunother Cancer. 2020. PMID: 32474414 Free PMC article.

2

Dual checkpoint blockade of CD47 and PD-L1 using an affinity-tuned bispecific antibody maximizes antitumor immunity.

Chen SH, Dominik PK, Stanfield J, Ding S, Yang W, Kurd N, Llewellyn R, Heyen J, Wang C, Melton Z, Van Blarcom T, Lindquist KC, Chaparro-Riggers J, Salek-Ardakani S. Chen SH, et al. Among authors: heyen j. J Immunother Cancer. 2021 Oct;9(10):e003464. doi: 10.1136/jitc-2021-003464. J Immunother Cancer. 2021. PMID: 34599020 Free PMC article.

3

Preclinical Development and Evaluation of Allogeneic CAR T Cells Targeting CD70 for the Treatment of Renal Cell Carcinoma.

Panowski SH, Srinivasan S, Tan N, Tacheva-Grigorova SK, Smith B, Mak YSL, Ning H, Villanueva J, Wijewarnasuriya D, Lang S, Melton Z, Ghosh A, Dusseaux M, Galetto R, Heyen JR, Sai T, Van Blarcom T, Chaparro-Riggers J, Sasu BJ. Panowski SH, et al. Among authors: heyen jr. Cancer Res. 2022 Jul 18;82(14):2610-2624. doi: 10.1158/0008-5472.CAN-21-2931. Cancer Res. 2022. PMID: 35294525

4

Characterization, biomarkers, and reversibility of a monoclonal antibody-induced immune complex disease in cynomolgus monkeys (Macaca fascicularis).

Heyen JR, Rojko J, Evans M, Brown TP, Bobrowski WF, Vitsky A, Dalton S, Tripathi N, Bollini SS, Johnson T, Lin JC, Khan N, Han B. Heyen JR, et al. Toxicol Pathol. 2014 Jun;42(4):765-73. doi: 10.1177/0192623314522559. Epub 2014 Mar 10. Toxicol Pathol. 2014. PMID: 24616262

5

Effects of chronic PPAR-agonist treatment on cardiac structure and function, blood pressure, and kidney in healthy sprague-dawley rats.

Blasi ER, Heyen J, Hemkens M, McHarg A, Ecelbarger CM, Tiwari S. Blasi ER, et al. Among authors: heyen j. PPAR Res. 2009;2009:237865. doi: 10.1155/2009/237865. Epub 2009 Jun 11. PPAR Res. 2009. PMID: 19536351 Free PMC article.

6

Cardiovascular effects in rats following exposure to a receptor tyrosine kinase inhibitor.

Aguirre SA, Heyen JR, Collette W 3rd, Bobrowski W, Blasi ER. Aguirre SA, et al. Toxicol Pathol. 2010 Apr;38(3):416-28. doi: 10.1177/0192623310364027. Epub 2010 Mar 15. Toxicol Pathol. 2010. PMID: 20231546

7

Pan-FGFR inhibition leads to blockade of FGF23 signaling, soft tissue mineralization, and cardiovascular dysfunction.

Yanochko GM, Vitsky A, Heyen JR, Hirakawa B, Lam JL, May J, Nichols T, Sace F, Trajkovic D, Blasi E. Yanochko GM, et al. Among authors: heyen jr. Toxicol Sci. 2013 Oct;135(2):451-64. doi: 10.1093/toxsci/kft161. Epub 2013 Jul 20. Toxicol Sci. 2013. PMID: 23872713

8

Mechanistic investigation of imatinib-induced cardiac toxicity and the involvement of c-Abl kinase.

Hu W, Lu S, McAlpine I, Jamieson JD, Lee DU, Marroquin LD, Heyen JR, Jessen BA. Hu W, et al. Among authors: heyen jr. Toxicol Sci. 2012 Sep;129(1):188-99. doi: 10.1093/toxsci/kfs192. Epub 2012 May 28. Toxicol Sci. 2012. PMID: 22641616

9

Therapy with TLR7 agonists induces lymphopenia: correlating pharmacology to mechanism in a mouse model.

Perkins H, Khodai T, Mechiche H, Colman P, Burden F, Laxton C, Horscroft N, Corey T, Rodrigues D, Rawal J, Heyen J, Fidock M, Westby M, Bright H. Perkins H, et al. Among authors: heyen j. J Clin Immunol. 2012 Oct;32(5):1082-92. doi: 10.1007/s10875-012-9687-y. Epub 2012 Apr 5. J Clin Immunol. 2012. PMID: 22476912

10

Sunitinib, a receptor tyrosine kinase inhibitor, increases blood pressure in rats without associated changes in cardiac structure and function.

Blasi E, Heyen J, Patyna S, Hemkens M, Ramirez D, John-Baptiste A, Steidl-Nichols J, McHarg A. Blasi E, et al. Among authors: heyen j. Cardiovasc Ther. 2012 Oct;30(5):287-94. doi: 10.1111/j.1755-5922.2011.00278.x. Epub 2011 May 31. Cardiovasc Ther. 2012. PMID: 21884012 Free article.

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