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Protein expression of the gp78 E3 ligase predicts poor breast cancer outcome based on race.
Singhal SK, Byun JS, Yan T, Yancey R, Caban A, Gil Hernandez S, Bufford S, Hewitt SM, Winfield J, Pradhan J, Mustkov V, McDonald JA, Pérez-Stable EJ, Nápoles AM, Vohra N, De Siervi A, Yates C, Davis MB, Yang M, Tsai YC, Weissman AM, Gardner K. Singhal SK, et al. Among authors: hewitt sm. JCI Insight. 2022 Jul 8;7(13):e157465. doi: 10.1172/jci.insight.157465. JCI Insight. 2022. PMID: 35639484 Free PMC article.
Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein.
Byun JS, Park S, Yi DI, Shin JH, Hernandez SG, Hewitt SM, Nicklaus MC, Peach ML, Guasch L, Tang B, Wakefield LM, Yan T, Caban A, Jones A, Kabbout M, Vohra N, Nápoles AM, Singhal S, Yancey R, De Siervi A, Gardner K. Byun JS, et al. Among authors: hewitt sm. Cell Death Dis. 2019 Sep 18;10(10):689. doi: 10.1038/s41419-019-1892-7. Cell Death Dis. 2019. PMID: 31534138 Free PMC article.
Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival.
Byun JS, Singhal SK, Park S, Yi DI, Yan T, Caban A, Jones A, Mukhopadhyay P, Gil SM, Hewitt SM, Newman L, Davis MB, Jenkins BD, Sepulveda JL, De Siervi A, Nápoles AM, Vohra NA, Gardner K. Byun JS, et al. Among authors: hewitt sm. Clin Cancer Res. 2020 Apr 15;26(8):1905-1914. doi: 10.1158/1078-0432.CCR-19-0875. Epub 2020 Jan 7. Clin Cancer Res. 2020. PMID: 31911546 Free PMC article.
Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis.
Marie KL, Sassano A, Yang HH, Michalowski AM, Michael HT, Guo T, Tsai YC, Weissman AM, Lee MP, Jenkins LM, Zaidi MR, Pérez-Guijarro E, Day CP, Ylaya K, Hewitt SM, Patel NL, Arnheiter H, Davis S, Meltzer PS, Merlino G, Mishra PJ. Marie KL, et al. Among authors: hewitt sm. Nat Commun. 2020 Jan 16;11(1):333. doi: 10.1038/s41467-019-14085-2. Nat Commun. 2020. PMID: 31949145 Free PMC article.
Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival.
Singhal SK, Byun JS, Park S, Yan T, Yancey R, Caban A, Hernandez SG, Hewitt SM, Boisvert H, Hennek S, Bobrow M, Ahmed MSU, White J, Yates C, Aukerman A, Vanguri R, Bareja R, Lenci R, Farré PL, De Siervi A, Nápoles AM, Vohra N, Gardner K. Singhal SK, et al. Among authors: hewitt sm. Commun Biol. 2021 Feb 1;4(1):150. doi: 10.1038/s42003-021-01651-y. Commun Biol. 2021. PMID: 33526872 Free PMC article.
Variation in breast cancer hormone receptor and HER2 levels by etiologic factors: a population-based analysis.
Sherman ME, Rimm DL, Yang XR, Chatterjee N, Brinton LA, Lissowska J, Peplonska B, Szeszenia-Dabrowska N, Zatonski W, Cartun R, Mandich D, Rymkiewicz G, Ligaj M, Lukaszek S, Kordek R, Kalaylioglu Z, Harigopal M, Charrette L, Falk RT, Richesson D, Anderson WF, Hewitt SM, García-Closas M. Sherman ME, et al. Among authors: hewitt sm. Int J Cancer. 2007 Sep 1;121(5):1079-85. doi: 10.1002/ijc.22812. Int J Cancer. 2007. PMID: 17487843 Free article.
Inhibition of mTOR signaling and clinical activity of metformin in oral premalignant lesions.
Gutkind JS, Molinolo AA, Wu X, Wang Z, Nachmanson D, Harismendy O, Alexandrov LB, Wuertz BR, Ondrey FG, Laronde D, Rock LD, Rosin M, Coffey C, Butler VD, Bengtson L, Hsu CH, Bauman JE, Hewitt SM, Cohen EE, Chow HS, Lippman SM, Szabo E. Gutkind JS, et al. Among authors: hewitt sm. JCI Insight. 2021 Sep 8;6(17):e147096. doi: 10.1172/jci.insight.147096. JCI Insight. 2021. PMID: 34255745 Free PMC article. Clinical Trial.
Interferon-gamma is quintessential for NOS2 and COX2 expression in ER- breast tumors that lead to poor outcome.
Cheng RYS, Ridnour LA, Wink AL, Gonzalez AL, Femino EL, Rittscher H, Somasundaram V, Heinz WF, Coutinho L, Rangel MC, Edmondson EF, Butcher D, Kinders RJ, Li X, Wong STC, McVicar DW, Anderson SK, Pore M, Hewitt SM, Billiar TR, Glynn SA, Chang JC, Lockett SJ, Ambs S, Wink DA. Cheng RYS, et al. Among authors: hewitt sm. Cell Death Dis. 2023 May 11;14(5):319. doi: 10.1038/s41419-023-05834-9. Cell Death Dis. 2023. PMID: 37169743 Free PMC article.
480 results