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Mitochondria are required for pro-ageing features of the senescent phenotype.
Correia-Melo C, Marques FD, Anderson R, Hewitt G, Hewitt R, Cole J, Carroll BM, Miwa S, Birch J, Merz A, Rushton MD, Charles M, Jurk D, Tait SW, Czapiewski R, Greaves L, Nelson G, Bohlooly-Y M, Rodriguez-Cuenca S, Vidal-Puig A, Mann D, Saretzki G, Quarato G, Green DR, Adams PD, von Zglinicki T, Korolchuk VI, Passos JF. Correia-Melo C, et al. Among authors: hewitt g, hewitt r. EMBO J. 2016 Apr 1;35(7):724-42. doi: 10.15252/embj.201592862. Epub 2016 Feb 4. EMBO J. 2016. PMID: 26848154 Free PMC article.
Wnt signaling potentiates nevogenesis.
Pawlikowski JS, McBryan T, van Tuyn J, Drotar ME, Hewitt RN, Maier AB, King A, Blyth K, Wu H, Adams PD. Pawlikowski JS, et al. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16009-14. doi: 10.1073/pnas.1303491110. Epub 2013 Sep 16. Proc Natl Acad Sci U S A. 2013. PMID: 24043806 Free PMC article.
Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest.
Dikovskaya D, Cole JJ, Mason SM, Nixon C, Karim SA, McGarry L, Clark W, Hewitt RN, Sammons MA, Zhu J, Athineos D, Leach JD, Marchesi F, van Tuyn J, Tait SW, Brock C, Morton JP, Wu H, Berger SL, Blyth K, Adams PD. Dikovskaya D, et al. Cell Rep. 2015 Sep 1;12(9):1483-96. doi: 10.1016/j.celrep.2015.07.055. Epub 2015 Aug 20. Cell Rep. 2015. PMID: 26299965 Free PMC article.
HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.
Rai TS, Cole JJ, Nelson DM, Dikovskaya D, Faller WJ, Vizioli MG, Hewitt RN, Anannya O, McBryan T, Manoharan I, van Tuyn J, Morrice N, Pchelintsev NA, Ivanov A, Brock C, Drotar ME, Nixon C, Clark W, Sansom OJ, Anderson KI, King A, Blyth K, Adams PD. Rai TS, et al. Genes Dev. 2014 Dec 15;28(24):2712-25. doi: 10.1101/gad.247528.114. Genes Dev. 2014. PMID: 25512559 Free PMC article.
Biomimetic microtopography to enhance osteogenesis in vitro.
Wilkinson A, Hewitt RN, McNamara LE, McCloy D, Dominic Meek RM, Dalby MJ. Wilkinson A, et al. Among authors: hewitt rn. Acta Biomater. 2011 Jul;7(7):2919-25. doi: 10.1016/j.actbio.2011.03.026. Epub 2011 Apr 1. Acta Biomater. 2011. PMID: 21459166
Mast cell activation disrupts interactions between endothelial cells and pericytes during early life allergic asthma.
Joulia R, Puttur F, Stölting H, Traves WJ, Entwistle LJ, Voitovich A, Garcia Martín M, Al-Sahaf M, Bonner K, Scotney E, Molyneaux PL, Hewitt RJ, Walker SA, Yates L, Saglani S, Lloyd CM. Joulia R, et al. Among authors: hewitt rj. J Clin Invest. 2024 Mar 15;134(6):e173676. doi: 10.1172/JCI173676. J Clin Invest. 2024. PMID: 38487999 Free PMC article.
Lentiviral expression of wild-type LAMA3A restores cell adhesion in airway basal cells from children with epidermolysis bullosa.
Lau CH, Rouhani MJ, Maughan EF, Orr JC, Kolluri KK, Pearce DR, Haughey EK, Sutton L, Flatau S, Balboa PL, Bageta ML, O'Callaghan C, Smith CM, Janes SM, Hewitt R, Petrof G, Martinez AE, McGrath JA, Butler CR, Hynds RE. Lau CH, et al. Among authors: hewitt r. Mol Ther. 2024 May 1;32(5):1497-1509. doi: 10.1016/j.ymthe.2024.02.032. Epub 2024 Feb 29. Mol Ther. 2024. PMID: 38429928 Free article.
481 results