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Considerations from an International Regulatory and Pharmaceutical Industry (IQ MPS Affiliate) Workshop on the Standardization of Complex In Vitro Models in Drug Development.
Tomlinson L, Ramsden D, Leite SB, Beken S, Bonzo JA, Brown P, Candarlioglu PL, Chan TS, Chen E, Choi CK, David R, Delrue N, Devine PJ, Ford K, Garcia MI, Gosset JR, Hewitt P, Homan K, Irrechukwu O, Kopec AK, Liras JL, Mandlekar S, Raczynski A, Sadrieh N, Sakatis MZ, Siegel J, Sung K, Sunyovszki I, Van Vleet TR, Ekert JE, Hardwick RN. Tomlinson L, et al. Among authors: hewitt p. Adv Biol (Weinh). 2023 Oct 9:e2300131. doi: 10.1002/adbi.202300131. Online ahead of print. Adv Biol (Weinh). 2023. PMID: 37814378
The evolving role of investigative toxicology in the pharmaceutical industry.
Pognan F, Beilmann M, Boonen HCM, Czich A, Dear G, Hewitt P, Mow T, Oinonen T, Roth A, Steger-Hartmann T, Valentin JP, Van Goethem F, Weaver RJ, Newham P. Pognan F, et al. Among authors: hewitt p. Nat Rev Drug Discov. 2023 Apr;22(4):317-335. doi: 10.1038/s41573-022-00633-x. Epub 2023 Feb 13. Nat Rev Drug Discov. 2023. PMID: 36781957 Free PMC article. Review.
Comparative Analysis of the Physiological and Transport Functions of Various Sources of Renal Proximal Tubule Cells Under Static and Fluidic Conditions in PhysioMimix{trade mark, serif} T12 Platform.
Sakolish C, Moyer HL, Tsai HD, Ford LC, Dickey AN, Bajaj P, Villenave R, Hewitt P, Ferguson SS, Stanko J, Rusyn I. Sakolish C, et al. Among authors: hewitt p. Drug Metab Dispos. 2024 Apr 16:DMD-AR-2023-001488. doi: 10.1124/dmd.124.001488. Online ahead of print. Drug Metab Dispos. 2024. PMID: 38626992 Free article.
Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids.
Chichagova V, Georgiou M, Carter M, Dorgau B, Hilgen G, Collin J, Queen R, Chung G, Ajeian J, Moya-Molina M, Kustermann S, Pognan F, Hewitt P, Schmitt M, Sernagor E, Armstrong L, Lako M. Chichagova V, et al. Among authors: hewitt p. J Cell Mol Med. 2023 Feb;27(3):435-445. doi: 10.1111/jcmm.17670. Epub 2023 Jan 16. J Cell Mol Med. 2023. PMID: 36644817 Free PMC article.
IL-2-mediated hepatotoxicity: knowledge gap identification based on the irAOP concept.
Roser LA, Sakellariou C, Lindstedt M, Neuhaus V, Dehmel S, Sommer C, Raasch M, Flandre T, Roesener S, Hewitt P, Parnham MJ, Sewald K, Schiffmann S. Roser LA, et al. Among authors: hewitt p. J Immunotoxicol. 2024 Dec;21(1):2332177. doi: 10.1080/1547691X.2024.2332177. Epub 2024 Apr 5. J Immunotoxicol. 2024. PMID: 38578203 Review.
399 results