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ROS1 rearrangements in non-small cell lung cancer: screening by immunohistochemistry using proportion of cells staining without intensity and excluding cases with MAPK pathway drivers improves test performance.
Prall OWJ, Browning J, Nastevski V, Caporarello S, Bates B, Hewitt CA, Arenas A, Lamb G, Howlett K, Arnolda R, Adeloju R, Stuart S, Xu H, Fellowes A, Fox SB. Prall OWJ, et al. Among authors: hewitt ca. Pathology. 2022 Apr;54(3):279-285. doi: 10.1016/j.pathol.2021.07.006. Epub 2021 Oct 8. Pathology. 2022. PMID: 34635319
Blood-based detection of RAS mutations to guide anti-EGFR therapy in colorectal cancer patients: concordance of results from circulating tumor DNA and tissue-based RAS testing.
Schmiegel W, Scott RJ, Dooley S, Lewis W, Meldrum CJ, Pockney P, Draganic B, Smith S, Hewitt C, Philimore H, Lucas A, Shi E, Namdarian K, Chan T, Acosta D, Ping-Chang S, Tannapfel A, Reinacher-Schick A, Uhl W, Teschendorf C, Wolters H, Stern J, Viebahn R, Friess H, Janssen KP, Nitsche U, Slotta-Huspenina J, Pohl M, Vangala D, Baraniskin A, Dockhorn-Dworniczak B, Hegewisch-Becker S, Ronga P, Edelstein DL, Jones FS, Hahn S, Fox SB. Schmiegel W, et al. Mol Oncol. 2017 Feb;11(2):208-219. doi: 10.1002/1878-0261.12023. Epub 2017 Jan 20. Mol Oncol. 2017. PMID: 28106345 Free PMC article. Clinical Trial.
Analysing DNA methylation using bisulphite pyrosequencing.
Mikeska T, Felsberg J, Hewitt CA, Dobrovic A. Mikeska T, et al. Among authors: hewitt ca. Methods Mol Biol. 2011;791:33-53. doi: 10.1007/978-1-61779-316-5_4. Methods Mol Biol. 2011. PMID: 21913070
55 results