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RNA-targeting strategies as a platform for ocular gene therapy.
Kumar S, Fry LE, Wang JH, Martin KR, Hewitt AW, Chen FK, Liu GS. Kumar S, et al. Among authors: hewitt aw. Prog Retin Eye Res. 2023 Jan;92:101110. doi: 10.1016/j.preteyeres.2022.101110. Epub 2022 Jul 13. Prog Retin Eye Res. 2023. PMID: 35840489 Review.
AAV-Mediated CRISPR/Cas Gene Editing of Retinal Cells In Vivo.
Hung SS, Chrysostomou V, Li F, Lim JK, Wang JH, Powell JE, Tu L, Daniszewski M, Lo C, Wong RC, Crowston JG, Pébay A, King AE, Bui BV, Liu GS, Hewitt AW. Hung SS, et al. Among authors: hewitt aw. Invest Ophthalmol Vis Sci. 2016 Jun 1;57(7):3470-6. doi: 10.1167/iovs.16-19316. Invest Ophthalmol Vis Sci. 2016. PMID: 27367513
Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.
Tedja MS, Wojciechowski R, Hysi PG, Eriksson N, Furlotte NA, Verhoeven VJM, Iglesias AI, Meester-Smoor MA, Tompson SW, Fan Q, Khawaja AP, Cheng CY, Höhn R, Yamashiro K, Wenocur A, Grazal C, Haller T, Metspalu A, Wedenoja J, Jonas JB, Wang YX, Xie J, Mitchell P, Foster PJ, Klein BEK, Klein R, Paterson AD, Hosseini SM, Shah RL, Williams C, Teo YY, Tham YC, Gupta P, Zhao W, Shi Y, Saw WY, Tai ES, Sim XL, Huffman JE, Polašek O, Hayward C, Bencic G, Rudan I, Wilson JF; CREAM Consortium; 23andMe Research Team; UK Biobank Eye and Vision Consortium; Joshi PK, Tsujikawa A, Matsuda F, Whisenhunt KN, Zeller T, van der Spek PJ, Haak R, Meijers-Heijboer H, van Leeuwen EM, Iyengar SK, Lass JH, Hofman A, Rivadeneira F, Uitterlinden AG, Vingerling JR, Lehtimäki T, Raitakari OT, Biino G, Concas MP, Schwantes-An TH, Igo RP Jr, Cuellar-Partida G, Martin NG, Craig JE, Gharahkhani P, Williams KM, Nag A, Rahi JS, Cumberland PM, Delcourt C, Bellenguez C, Ried JS, Bergen AA, Meitinger T, Gieger C, Wong TY, Hewitt AW, Mackey DA, Simpson CL, Pfeiffer N, Pärssinen O, Baird PN, Vitart V, Amin N, van Duijn CM, Bailey-Wilson JE, Young TL, Saw SM, Stambolian D, MacGregor S, Guggenheim JA, Tung JY, Hammon… See abstract for full author list ➔ Tedja MS, et al. Among authors: hewitt aw. Nat Genet. 2018 Jun;50(6):834-848. doi: 10.1038/s41588-018-0127-7. Epub 2018 May 28. Nat Genet. 2018. PMID: 29808027 Free PMC article.
The current state of stem cell therapy for ocular disease.
Bobba S, Di Girolamo N, Munsie M, Chen F, Pébay A, Harkin D, Hewitt AW, O'Connor M, McLenachan S, Shadforth AMA, Watson SL. Bobba S, et al. Among authors: hewitt aw. Exp Eye Res. 2018 Dec;177:65-75. doi: 10.1016/j.exer.2018.07.019. Epub 2018 Jul 17. Exp Eye Res. 2018. PMID: 30029023 Review.
Gene therapy for visual loss: Opportunities and concerns.
Lee JH, Wang JH, Chen J, Li F, Edwards TL, Hewitt AW, Liu GS. Lee JH, et al. Among authors: hewitt aw. Prog Retin Eye Res. 2019 Jan;68:31-53. doi: 10.1016/j.preteyeres.2018.08.003. Epub 2018 Aug 29. Prog Retin Eye Res. 2019. PMID: 30170104 Review.
Utility of Self-Destructing CRISPR/Cas Constructs for Targeted Gene Editing in the Retina.
Li F, Hung SSC, Mohd Khalid MKN, Wang JH, Chrysostomou V, Wong VHY, Singh V, Wing K, Tu L, Bender JA, Pébay A, King AE, Cook AL, Wong RCB, Bui BV, Hewitt AW, Liu GS. Li F, et al. Among authors: hewitt aw. Hum Gene Ther. 2019 Nov;30(11):1349-1360. doi: 10.1089/hum.2019.021. Epub 2019 Oct 25. Hum Gene Ther. 2019. PMID: 31373227
428 results