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Page 1
Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements.
Burbage M, Rocañín-Arjó A, Baudon B, Arribas YA, Merlotti A, Rookhuizen DC, Heurtebise-Chrétien S, Ye M, Houy A, Burgdorf N, Suarez G, Gros M, Sadacca B, Carrascal M, Garmilla A, Bohec M, Baulande S, Lombard B, Loew D, Waterfall JJ, Stern MH, Goudot C, Amigorena S. Burbage M, et al. Among authors: heurtebise chretien s. Sci Immunol. 2023 Feb 3;8(80):eabm6360. doi: 10.1126/sciimmunol.abm6360. Epub 2023 Feb 3. Sci Immunol. 2023. PMID: 36735776
Rare Coding Variants in ANGPTL6 Are Associated with Familial Forms of Intracranial Aneurysm.
Bourcier R, Le Scouarnec S, Bonnaud S, Karakachoff M, Bourcereau E, Heurtebise-Chrétien S, Menguy C, Dina C, Simonet F, Moles A, Lenoble C, Lindenbaum P, Chatel S, Isidor B, Génin E, Deleuze JF, Schott JJ, Le Marec H; ICAN Study Group; Loirand G, Desal H, Redon R. Bourcier R, et al. Among authors: heurtebise chretien s. Am J Hum Genet. 2018 Jan 4;102(1):133-141. doi: 10.1016/j.ajhg.2017.12.006. Am J Hum Genet. 2018. PMID: 29304371 Free PMC article.
Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation.
Gehrmann U, Burbage M, Zueva E, Goudot C, Esnault C, Ye M, Carpier JM, Burgdorf N, Hoyler T, Suarez G, Joannas L, Heurtebise-Chrétien S, Durand S, Panes R, Bellemare-Pelletier A, Sáez PJ, Aprahamian F, Lefevre D, Adoue V, Zine El Aabidine A, Muhammad Ahmad M, Hivroz C, Joffre O, Cammas F, Kroemer G, Gagnon E, Andrau JC, Amigorena S. Gehrmann U, et al. Among authors: heurtebise chretien s. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25839-25849. doi: 10.1073/pnas.1901639116. Epub 2019 Nov 27. Proc Natl Acad Sci U S A. 2019. PMID: 31776254 Free PMC article.
Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity.
Kozik P, Gros M, Itzhak DN, Joannas L, Heurtebise-Chrétien S, Krawczyk PA, Rodríguez-Silvestre P, Alloatti A, Magalhaes JG, Del Nery E, Borner GHH, Amigorena S. Kozik P, et al. Among authors: heurtebise chretien s. Cell Rep. 2020 Jul 14;32(2):107905. doi: 10.1016/j.celrep.2020.107905. Cell Rep. 2020. PMID: 32668257 Free PMC article.
Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation.
Gros M, Segura E, Rookhuizen DC, Baudon B, Heurtebise-Chrétien S, Burgdorf N, Maurin M, Kapp EA, Simpson RJ, Kozik P, Villadangos JA, Bertrand MJM, Burbage M, Amigorena S. Gros M, et al. Among authors: heurtebise chretien s. Cell Rep. 2022 Aug 16;40(7):111205. doi: 10.1016/j.celrep.2022.111205. Cell Rep. 2022. PMID: 35977488 Free PMC article.
Noncanonical splicing junctions between exons and transposable elements represent a source of immunogenic recurrent neo-antigens in patients with lung cancer.
Merlotti A, Sadacca B, Arribas YA, Ngoma M, Burbage M, Goudot C, Houy A, Rocañín-Arjó A, Lalanne A, Seguin-Givelet A, Lefevre M, Heurtebise-Chrétien S, Baudon B, Oliveira G, Loew D, Carrascal M, Wu CJ, Lantz O, Stern MH, Girard N, Waterfall JJ, Amigorena S. Merlotti A, et al. Among authors: heurtebise chretien s. Sci Immunol. 2023 Feb 3;8(80):eabm6359. doi: 10.1126/sciimmunol.abm6359. Epub 2023 Feb 3. Sci Immunol. 2023. PMID: 36735774
Selective control of transposable element expression during T cell exhaustion and anti-PD-1 treatment.
Bonté PE, Metoikidou C, Heurtebise-Chretien S, Arribas YA, Sutra Del Galy A, Ye M, Niborski LL, Zueva E, Piaggio E, Seguin-Givelet A, Girard N, Alanio C, Burbage M, Goudot C, Amigorena S. Bonté PE, et al. Among authors: heurtebise chretien s. Sci Immunol. 2023 Oct 27;8(88):eadf8838. doi: 10.1126/sciimmunol.adf8838. Epub 2023 Oct 27. Sci Immunol. 2023. PMID: 37889984
Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis.
Carbone ML, Chadeuf G, Heurtebise-Chrétien S, Prieur X, Quillard T, Goueffic Y, Vaillant N, Rio M, Castan L, Durand M, Baron-Menguy C, Aureille J, Desfrançois J, Tesse A, Torres RM, Loirand G. Carbone ML, et al. Among authors: heurtebise chretien s. J Clin Invest. 2017 Dec 1;127(12):4516-4526. doi: 10.1172/JCI92702. Epub 2017 Nov 13. J Clin Invest. 2017. PMID: 29130930 Free PMC article.