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A platform trial of neoadjuvant and adjuvant antitumor vaccination alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectable pancreatic adenocarcinoma.
Heumann T, Judkins C, Li K, Lim SJ, Hoare J, Parkinson R, Cao H, Zhang T, Gai J, Celiker B, Zhu Q, McPhaul T, Durham J, Purtell K, Klein R, Laheru D, De Jesus-Acosta A, Le DT, Narang A, Anders R, Burkhart R, Burns W, Soares K, Wolfgang C, Thompson E, Jaffee E, Wang H, He J, Zheng L. Heumann T, et al. Nat Commun. 2023 Jun 20;14(1):3650. doi: 10.1038/s41467-023-39196-9. Nat Commun. 2023. PMID: 37339979 Free PMC article.
Barcoding intracellular reverse transcription enables high-throughput phenotype-coupled T cell receptor analyses.
Jayaraman S, Montagne JM, Nirschl TR, Marcisak E, Johnson J, Huff A, Hsiao MH, Nauroth J, Heumann T, Zarif JC, Jaffee EM, Azad N, Fertig EJ, Zaidi N, Larman HB. Jayaraman S, et al. Among authors: heumann t. Cell Rep Methods. 2023 Oct 23;3(10):100600. doi: 10.1016/j.crmeth.2023.100600. Epub 2023 Sep 29. Cell Rep Methods. 2023. PMID: 37776855 Free PMC article.
A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence.
Heumann TR, Baretti M, Sugar EA, Durham JN, Linden S, Lopez-Vidal TY, Leatherman J, Cope L, Sharma A, Weekes CD, O'Dwyer PJ, Reiss KA, Monga DK, Ahuja N, Azad NS. Heumann TR, et al. Clin Epigenetics. 2022 Dec 3;14(1):166. doi: 10.1186/s13148-022-01367-8. Clin Epigenetics. 2022. PMID: 36463226 Free PMC article. Clinical Trial.
Bone marrow-derived angiogenic cells restore lung alveolar and vascular structure after neonatal hyperoxia in infant mice.
Balasubramaniam V, Ryan SL, Seedorf GJ, Roth EV, Heumann TR, Yoder MC, Ingram DA, Hogan CJ, Markham NE, Abman SH. Balasubramaniam V, et al. Among authors: heumann tr. Am J Physiol Lung Cell Mol Physiol. 2010 Mar;298(3):L315-23. doi: 10.1152/ajplung.00089.2009. Epub 2009 Dec 11. Am J Physiol Lung Cell Mol Physiol. 2010. PMID: 20008116 Free PMC article.