Hettinga KA - Search Results

1

Introduction of Heated Cow's Milk Protein in Challenge-Proven Cow's Milk Allergic Children: The iAGE Study.

de Jong NW, van Splunter ME, Emons JAM, Hettinga KA, Gerth van Wijk R, Wichers HJ, Savelkoul HFJ, Sprikkelman AB, van Neerven RJJ, Liu L, van der Meulen G, Herpertz I, Duijvestijn YCM, Breukels M, Brouwer MI, Schilperoord J, van Doorn O, Vlieg-Boerstra B, van den Berg J, Pellis L, Terlouw S, Hendriks AI, Schreurs MWJ, van Boven FE, Arends NJT. de Jong NW, et al. Among authors: hettinga ka. Nutrients. 2022 Jan 31;14(3):629. doi: 10.3390/nu14030629. Nutrients. 2022. PMID: 35276990 Free PMC article.

2

The decrease in the IgG-binding capacity of intensively dry heated whey proteins is associated with intense Maillard reaction, structural changes of the proteins and formation of RAGE-ligands.

Liu F, Teodorowicz M, van Boekel MA, Wichers HJ, Hettinga KA. Liu F, et al. Among authors: hettinga ka. Food Funct. 2016 Jan;7(1):239-49. doi: 10.1039/c5fo00718f. Food Funct. 2016. PMID: 26524422

3

A proteomics-based identification of putative biomarkers for disease in bovine milk.

van Altena SE, de Klerk B, Hettinga KA, van Neerven RJ, Boeren S, Savelkoul HF, Tijhaar EJ. van Altena SE, et al. Among authors: hettinga ka. Vet Immunol Immunopathol. 2016 Jun;174:11-8. doi: 10.1016/j.vetimm.2016.04.005. Epub 2016 Apr 8. Vet Immunol Immunopathol. 2016. PMID: 27185258 Free article.

4

Generation of Soluble Advanced Glycation End Products Receptor (sRAGE)-Binding Ligands during Extensive Heat Treatment of Whey Protein/Lactose Mixtures Is Dependent on Glycation and Aggregation.

Liu F, Teodorowicz M, Wichers HJ, van Boekel MA, Hettinga KA. Liu F, et al. Among authors: hettinga ka. J Agric Food Chem. 2016 Aug 24;64(33):6477-86. doi: 10.1021/acs.jafc.6b02674. Epub 2016 Aug 15. J Agric Food Chem. 2016. PMID: 27460534

5

Hydrophobicity and aggregation, but not glycation, are key determinants for uptake of thermally processed β-lactoglobulin by THP-1 macrophages.

Deng Y, Govers C, Bastiaan-Net S, van der Hulst N, Hettinga K, Wichers HJ. Deng Y, et al. Food Res Int. 2019 Jun;120:102-113. doi: 10.1016/j.foodres.2019.01.038. Epub 2019 Jan 22. Food Res Int. 2019. PMID: 31000219 Free article.

6

Differential Effects of Dry vs. Wet Heating of β-Lactoglobulin on Formation of sRAGE Binding Ligands and sIgE Epitope Recognition.

Zenker HE, Ewaz A, Deng Y, Savelkoul HFJ, van Neerven RJJ, De Jong NW, Wichers HJ, Hettinga KA, Teodorowicz M. Zenker HE, et al. Among authors: hettinga ka. Nutrients. 2019 Jun 25;11(6):1432. doi: 10.3390/nu11061432. Nutrients. 2019. PMID: 31242665 Free PMC article.

7

Maternal Allergy and the Presence of Nonhuman Proteinaceous Molecules in Human Milk.

Dekker PM, Boeren S, Wijga AH, Koppelman GH, Vervoort JJM, Hettinga KA. Dekker PM, et al. Among authors: hettinga ka. Nutrients. 2020 Apr 22;12(4):1169. doi: 10.3390/nu12041169. Nutrients. 2020. PMID: 32331315 Free PMC article.

8

Heat treatment of β-lactoglobulin affects its digestion and translocation in the upper digestive tract.

Deng Y, Govers C, Tomassen M, Hettinga K, Wichers HJ. Deng Y, et al. Food Chem. 2020 Nov 15;330:127184. doi: 10.1016/j.foodchem.2020.127184. Epub 2020 Jun 4. Food Chem. 2020. PMID: 32531635

9

Binding of CML-Modified as Well as Heat-Glycated β-lactoglobulin to Receptors for AGEs Is Determined by Charge and Hydrophobicity.

Zenker HE, Teodorowicz M, Ewaz A, van Neerven RJJ, Savelkoul HFJ, De Jong NW, Wichers HJ, Hettinga KA. Zenker HE, et al. Among authors: hettinga ka. Int J Mol Sci. 2020 Jun 26;21(12):4567. doi: 10.3390/ijms21124567. Int J Mol Sci. 2020. PMID: 32604964 Free PMC article.

10

Hydrophobicity drives receptor-mediated uptake of heat-processed proteins by THP-1 macrophages and dendritic cells, but not cytokine responses.

Deng Y, Govers C, Teodorowicz M, Liobyte I, De Simone I, Hettinga K, Wichers HJ. Deng Y, et al. PLoS One. 2020 Aug 14;15(8):e0236212. doi: 10.1371/journal.pone.0236212. eCollection 2020. PLoS One. 2020. PMID: 32797100 Free PMC article.

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