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A bacteriophage endolysin that eliminates intracellular streptococci.
Shen Y, Barros M, Vennemann T, Gallagher DT, Yin Y, Linden SB, Heselpoth RD, Spencer DJ, Donovan DM, Moult J, Fischetti VA, Heinrich F, Lösche M, Nelson DC. Shen Y, et al. Among authors: heselpoth rd. Elife. 2016 Mar 15;5:e13152. doi: 10.7554/eLife.13152. Elife. 2016. PMID: 26978792 Free PMC article.
X-ray crystal structure of the streptococcal specific phage lysin PlyC.
McGowan S, Buckle AM, Mitchell MS, Hoopes JT, Gallagher DT, Heselpoth RD, Shen Y, Reboul CF, Law RH, Fischetti VA, Whisstock JC, Nelson DC. McGowan S, et al. Among authors: heselpoth rd. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12752-7. doi: 10.1073/pnas.1208424109. Epub 2012 Jul 17. Proc Natl Acad Sci U S A. 2012. PMID: 22807482 Free PMC article.
High avidity drives the interaction between the streptococcal C1 phage endolysin, PlyC, with the cell surface carbohydrates of Group A Streptococcus.
Broendum SS, Williams DE, Hayes BK, Kraus F, Fodor J, Clifton BE, Geert Volbeda A, Codee JDC, Riley BT, Drinkwater N, Farrow KA, Tsyganov K, Heselpoth RD, Nelson DC, Jackson CJ, Buckle AM, McGowan S. Broendum SS, et al. Among authors: heselpoth rd. Mol Microbiol. 2021 Aug;116(2):397-415. doi: 10.1111/mmi.14719. Epub 2021 Apr 3. Mol Microbiol. 2021. PMID: 33756056 Free article.
18 results