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Year Number of Results
2010 1
2012 2
2013 2
2014 2
2015 1
2016 1
2017 2
2018 6
2019 4
2020 3
2021 4
2022 3
2023 2
2024 1

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31 results

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Page 1
The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis.
Hazari Y, Urra H, Garcia Lopez VA, Diaz J, Tamburini G, Milani M, Pihan P, Durand S, Aprahamia F, Baxter R, Huang M, Dong XC, Vihinen H, Batista-Gonzalez A, Godoy P, Criollo A, Ratziu V, Foufelle F, Hengstler JG, Jokitalo E, Bailly-Maitre B, Maiers JL, Plate L, Kroemer G, Hetz C. Hazari Y, et al. Among authors: urra h. bioRxiv [Preprint]. 2023 May 2:2023.05.02.538835. doi: 10.1101/2023.05.02.538835. bioRxiv. 2023. PMID: 37205565 Free PMC article. Preprint.
Assays to Study IRE1 Activation and Signaling.
Moraga P, Aravena R, Urra H, Hetz C. Moraga P, et al. Among authors: urra h. Methods Mol Biol. 2022;2378:141-168. doi: 10.1007/978-1-0716-1732-8_10. Methods Mol Biol. 2022. PMID: 34985699
Mutation in protein disulfide isomerase A3 causes neurodevelopmental defects by disturbing endoplasmic reticulum proteostasis.
Bilches Medinas D, Malik S, Yıldız-Bölükbaşı E, Borgonovo J, Saaranen MJ, Urra H, Pulgar E, Afzal M, Contreras D, Wright MT, Bodaleo F, Quiroz G, Rozas P, Mumtaz S, Díaz R, Rozas C, Cabral-Miranda F, Piña R, Valenzuela V, Uyan O, Reardon C, Woehlbier U, Brown RH, Sena-Esteves M, Gonzalez-Billault C, Morales B, Plate L, Ruddock LW, Concha ML, Hetz C, Tolun A. Bilches Medinas D, et al. Among authors: urra h. EMBO J. 2022 Dec 17;41(2):e105531. doi: 10.15252/embj.2020105531. Epub 2021 Dec 14. EMBO J. 2022. PMID: 34904718 Free PMC article.
Control of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1.
Pihán P, Lisbona F, Borgonovo J, Edwards-Jorquera S, Nunes-Hasler P, Castillo K, Kepp O, Urra H, Saarnio S, Vihinen H, Carreras-Sureda A, Forveille S, Sauvat A, De Giorgis D, Pupo A, Rodríguez DA, Quarato G, Sagredo A, Lourido F, Letai A, Latorre R, Kroemer G, Demaurex N, Jokitalo E, Concha ML, Glavic Á, Green DR, Hetz C. Pihán P, et al. Among authors: urra h. Sci Adv. 2021 Nov 12;7(46):eabe5469. doi: 10.1126/sciadv.abe5469. Epub 2021 Nov 12. Sci Adv. 2021. PMID: 34767445 Free PMC article.
BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.
Rodriguez DA, Zamorano S, Lisbona F, Rojas-Rivera D, Urra H, Cubillos-Ruiz JR, Armisen R, Henriquez DR, Cheng EH, Letek M, Vaisar T, Irrazabal T, Gonzalez-Billault C, Letai A, Pimentel-Muiños FX, Kroemer G, Hetz C. Rodriguez DA, et al. Among authors: urra h. EMBO J. 2021 Sep 15;40(18):e109146. doi: 10.15252/embj.2021109146. EMBO J. 2021. PMID: 34523136 Free PMC article.
Author Correction: IRE1α governs cytoskeleton remodeling and cell migration through a direct interaction with filamin A.
Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic Á, Gonzalez-Billault C, Hetz C. Urra H, et al. Nat Cell Biol. 2021 May;23(5):577. doi: 10.1038/s41556-021-00673-2. Nat Cell Biol. 2021. PMID: 33907311 No abstract available.
31 results