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Nicotinic-acid derivative BGP-15 improves diastolic function in a rabbit model of atherosclerotic cardiomyopathy.
Priksz D, Lampe N, Kovacs A, Herwig M, Bombicz M, Varga B, Wilisicz T, Szilvassy J, Posa A, Kiss R, Gesztelyi R, Raduly A, Szekeres R, Sieme M, Papp Z, Toth A, Hamdani N, Szilvassy Z, Juhasz B. Priksz D, et al. Among authors: herwig m. Br J Pharmacol. 2022 May;179(10):2240-2258. doi: 10.1111/bph.15749. Epub 2022 Feb 5. Br J Pharmacol. 2022. PMID: 34811751 Free article.
Stretch-induced compliance: a novel adaptive biological mechanism following acute cardiac load.
Leite-Moreira AM, Almeida-Coelho J, Neves JS, Pires AL, Ferreira-Martins J, Castro-Ferreira R, Ladeiras-Lopes R, Conceição G, Miranda-Silva D, Rodrigues P, Hamdani N, Herwig M, Falcão-Pires I, Paulus WJ, Linke WA, Lourenço AP, Leite-Moreira AF. Leite-Moreira AM, et al. Among authors: herwig m. Cardiovasc Res. 2018 Apr 1;114(5):656-667. doi: 10.1093/cvr/cvy026. Cardiovasc Res. 2018. PMID: 29401264
Diastolic dysfunction is initiated by cardiomyocyte impairment ahead of endothelial dysfunction due to increased oxidative stress and inflammation in an experimental prediabetes model.
Waddingham MT, Sonobe T, Tsuchimochi H, Edgley AJ, Sukumaran V, Chen YC, Hansra SS, Schwenke DO, Umetani K, Aoyama K, Yagi N, Kelly DJ, Gaderi S, Herwig M, Kolijn D, Mügge A, Paulus WJ, Ogo T, Shirai M, Hamdani N, Pearson JT. Waddingham MT, et al. Among authors: herwig m. J Mol Cell Cardiol. 2019 Dec;137:119-131. doi: 10.1016/j.yjmcc.2019.10.005. Epub 2019 Oct 28. J Mol Cell Cardiol. 2019. PMID: 31669609 Free article.
Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D.
Herwig M, Kolijn D, Lódi M, Hölper S, Kovács Á, Papp Z, Jaquet K, Haldenwang P, Dos Remedios C, Reusch PH, Mügge A, Krüger M, Fielitz J, Linke WA, Hamdani N. Herwig M, et al. Front Physiol. 2020 Apr 15;11:240. doi: 10.3389/fphys.2020.00240. eCollection 2020. Front Physiol. 2020. PMID: 32351396 Free PMC article.
CaMKII activity contributes to homeometric autoregulation of the heart: A novel mechanism for the Anrep effect.
Reil JC, Reil GH, Kovács Á, Sequeira V, Waddingham MT, Lodi M, Herwig M, Ghaderi S, Kreusser MM, Papp Z, Voigt N, Dobrev D, Meyhöfer S, Langer HF, Maier LS, Linz D, Mügge A, Hohl M, Steendijk P, Hamdani N. Reil JC, et al. Among authors: herwig m. J Physiol. 2020 Aug;598(15):3129-3153. doi: 10.1113/JP279607. Epub 2020 Jun 14. J Physiol. 2020. PMID: 32394454 Free PMC article.
Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation.
Kolijn D, Pabel S, Tian Y, Lódi M, Herwig M, Carrizzo A, Zhazykbayeva S, Kovács Á, Fülöp GÁ, Falcão-Pires I, Reusch PH, Linthout SV, Papp Z, van Heerebeek L, Vecchione C, Maier LS, Ciccarelli M, Tschöpe C, Mügge A, Bagi Z, Sossalla S, Hamdani N. Kolijn D, et al. Among authors: herwig m. Cardiovasc Res. 2021 Jan 21;117(2):495-507. doi: 10.1093/cvr/cvaa123. Cardiovasc Res. 2021. PMID: 32396609
Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator.
Kolijn D, Kovács Á, Herwig M, Lódi M, Sieme M, Alhaj A, Sandner P, Papp Z, Reusch PH, Haldenwang P, Falcão-Pires I, Linke WA, Jaquet K, Van Linthout S, Mügge A, Tschöpe C, Hamdani N. Kolijn D, et al. Among authors: herwig m. Front Physiol. 2020 May 25;11:345. doi: 10.3389/fphys.2020.00345. eCollection 2020. Front Physiol. 2020. PMID: 32523538 Free PMC article.
C-type natriuretic peptide moderates titin-based cardiomyocyte stiffness.
Michel K, Herwig M, Werner F, Špiranec Spes K, Abeßer M, Schuh K, Dabral S, Mügge A, Baba HA, Skryabin BV, Hamdani N, Kuhn M. Michel K, et al. Among authors: herwig m. JCI Insight. 2020 Nov 19;5(22):e139910. doi: 10.1172/jci.insight.139910. JCI Insight. 2020. PMID: 33055420 Free PMC article.
78 results