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Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function.
Michel M, Benítez-Buelga C, Calvo PA, Hanna BMF, Mortusewicz O, Masuyer G, Davies J, Wallner O, Sanjiv K, Albers JJ, Castañeda-Zegarra S, Jemth AS, Visnes T, Sastre-Perona A, Danda AN, Homan EJ, Marimuthu K, Zhenjun Z, Chi CN, Sarno A, Wiita E, von Nicolai C, Komor AJ, Rajagopal V, Müller S, Hank EC, Varga M, Scaletti ER, Pandey M, Karsten S, Haslene-Hox H, Loevenich S, Marttila P, Rasti A, Mamonov K, Ortis F, Schömberg F, Loseva O, Stewart J, D'Arcy-Evans N, Koolmeister T, Henriksson M, Michel D, de Ory A, Acero L, Calvete O, Scobie M, Hertweck C, Vilotijevic I, Kalderén C, Osorio A, Perona R, Stolz A, Stenmark P, Berglund UW, de Vega M, Helleday T. Michel M, et al. Among authors: hertweck c. Science. 2022 Jun 24;376(6600):1471-1476. doi: 10.1126/science.abf8980. Epub 2022 Jun 23. Science. 2022. PMID: 35737787
Natural products from reconstructed bacterial genomes of the Middle and Upper Paleolithic.
Klapper M, Hübner A, Ibrahim A, Wasmuth I, Borry M, Haensch VG, Zhang S, Al-Jammal WK, Suma H, Fellows Yates JA, Frangenberg J, Velsko IM, Chowdhury S, Herbst R, Bratovanov EV, Dahse HM, Horch T, Hertweck C, González Morales MR, Straus LG, Vilotijevic I, Warinner C, Stallforth P. Klapper M, et al. Among authors: hertweck c. Science. 2023 May 12;380(6645):619-624. doi: 10.1126/science.adf5300. Epub 2023 May 4. Science. 2023. PMID: 37141315
Streptomyces polyketides mediate bacteria-fungi interactions across soil environments.
Krespach MKC, Stroe MC, Netzker T, Rosin M, Zehner LM, Komor AJ, Beilmann JM, Krüger T, Scherlach K, Kniemeyer O, Schroeckh V, Hertweck C, Brakhage AA. Krespach MKC, et al. Among authors: hertweck c. Nat Microbiol. 2023 Jul;8(7):1348-1361. doi: 10.1038/s41564-023-01382-2. Epub 2023 Jun 15. Nat Microbiol. 2023. PMID: 37322111 Free PMC article.
A mutualistic bacterium rescues a green alga from an antagonist.
Carrasco Flores D, Hotter V, Vuong T, Hou Y, Bando Y, Scherlach K, Burgunter-Delamare B, Hermenau R, Komor AJ, Aiyar P, Rose M, Sasso S, Arndt HD, Hertweck C, Mittag M. Carrasco Flores D, et al. Among authors: hertweck c. Proc Natl Acad Sci U S A. 2024 Apr 9;121(15):e2401632121. doi: 10.1073/pnas.2401632121. Epub 2024 Apr 3. Proc Natl Acad Sci U S A. 2024. PMID: 38568970 Free PMC article.
374 results