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An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.
Vugler A, O'Connell J, Nguyen MA, Weitz D, Leeuw T, Hickford E, Verbitsky A, Ying X, Rehberg M, Carrington B, Merriman M, Moss A, Nicholas JM, Stanley P, Wright S, Bourne T, Foricher Y, Brookings D, Horsley H, Herrmann M, Rao S, Kohlmann M, Florian P. Vugler A, et al. Among authors: herrmann m. Front Pharmacol. 2022 Nov 16;13:1037983. doi: 10.3389/fphar.2022.1037983. eCollection 2022. Front Pharmacol. 2022. PMID: 36467083 Free PMC article.
Additive efficacy of a bispecific anti-TNF/IL-6 nanobody compound in translational models of rheumatoid arthritis.
Biesemann N, Margerie D, Asbrand C, Rehberg M, Savova V, Agueusop I, Klemmer D, Ding-Pfennigdorff D, Schwahn U, Dudek M, Heyninck K, De Tavernier E, Cornelis S, Kohlmann M, Nestle FO, Herrmann M. Biesemann N, et al. Among authors: herrmann m. Sci Transl Med. 2023 Feb;15(681):eabq4419. doi: 10.1126/scitranslmed.abq4419. Epub 2023 Feb 1. Sci Transl Med. 2023. PMID: 36724239
Glucose transporter 1 in rheumatoid arthritis and autoimmunity.
Zezina E, Sercan-Alp O, Herrmann M, Biesemann N. Zezina E, et al. Among authors: herrmann m. Wiley Interdiscip Rev Syst Biol Med. 2020 Jul;12(4):e1483. doi: 10.1002/wsbm.1483. Epub 2020 Feb 21. Wiley Interdiscip Rev Syst Biol Med. 2020. PMID: 32084302 Review.
Neutrophilic granulocyte-derived B-cell activating factor supports B cells in skin lesions in hidradenitis suppurativa.
Sabat R, Šimaitė D, Gudjonsson JE, Brembach TC, Witte K, Krause T, Kokolakis G, Bartnik E, Nikolaou C, Rill N, Coulibaly B, Levin C, Herrmann M, Salinas G, Leeuw T, Volk HD, Ghoreschi K, Wolk K. Sabat R, et al. Among authors: herrmann m. J Allergy Clin Immunol. 2023 Apr;151(4):1015-1026. doi: 10.1016/j.jaci.2022.10.034. Epub 2022 Dec 5. J Allergy Clin Immunol. 2023. PMID: 36481267
1,862 results