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The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression.
Peñuelas-Haro I, Espinosa-Sotelo R, Crosas-Molist E, Herranz-Itúrbide M, Caballero-Díaz D, Alay A, Solé X, Ramos E, Serrano T, Martínez-Chantar ML, Knaus UG, Cuezva JM, Zorzano A, Bertran E, Fabregat I. Peñuelas-Haro I, et al. Among authors: herranz iturbide m. Hepatology. 2023 Aug 1;78(2):416-433. doi: 10.1002/hep.32702. Epub 2022 Sep 17. Hepatology. 2023. PMID: 35920301 Free PMC article.
NADPH oxidase 4 (Nox4) deletion accelerates liver regeneration in mice.
Herranz-Itúrbide M, López-Luque J, Gonzalez-Sanchez E, Caballero-Díaz D, Crosas-Molist E, Martín-Mur B, Gut M, Esteve-Codina A, Jaquet V, Jiang JX, Török NJ, Fabregat I. Herranz-Itúrbide M, et al. Redox Biol. 2021 Apr;40:101841. doi: 10.1016/j.redox.2020.101841. Epub 2020 Dec 23. Redox Biol. 2021. PMID: 33493901 Free PMC article.