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Page 1
Structure-based discovery of LpxC inhibitors.
Zhang J, Chan A, Lippa B, Cross JB, Liu C, Yin N, Romero JA, Lawrence J, Heney R, Herradura P, Goss J, Clark C, Abel C, Zhang Y, Poutsiaka KM, Epie F, Conrad M, Mahamoon A, Nguyen K, Chavan A, Clark E, Li TC, Cheng RK, Wood M, Andersen OA, Brooks M, Kwong J, Barker J, Parr IB, Gu Y, Ryan MD, Coleman S, Metcalf CA 3rd. Zhang J, et al. Among authors: herradura p. Bioorg Med Chem Lett. 2017 Apr 15;27(8):1670-1680. doi: 10.1016/j.bmcl.2017.03.006. Epub 2017 Mar 6. Bioorg Med Chem Lett. 2017. PMID: 28302397
Conformationally restricted analogs of deoxynegamycin.
Raju B, Anandan S, Gu S, Herradura P, O'Dowd H, Kim B, Gomez M, Hackbarth C, Wu C, Wang W, Yuan Z, White R, Trias J, Patel DV. Raju B, et al. Among authors: herradura p. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3103-7. doi: 10.1016/j.bmcl.2004.04.036. Bioorg Med Chem Lett. 2004. PMID: 15149653
Structure-Activity Relationship Studies of a Series of Semisynthetic Lipopeptides Leading to the Discovery of Surotomycin, a Novel Cyclic Lipopeptide Being Developed for the Treatment of Clostridium difficile-Associated Diarrhea.
Yin N, Li J, He Y, Herradura P, Pearson A, Mesleh MF, Mascio CT, Howland K, Steenbergen J, Thorne GM, Citron D, Van Praagh AD, Mortin LI, Keith D, Silverman J, Metcalf C. Yin N, et al. Among authors: herradura p. J Med Chem. 2015 Jun 25;58(12):5137-42. doi: 10.1021/acs.jmedchem.5b00366. Epub 2015 Jun 3. J Med Chem. 2015. PMID: 25993059
Randomized clinical trial to assess the efficacy of a comprehensive programme of secondary prevention of cardiovascular disease in general practice: the PREseAP study.
Brotons C, Soriano N, Moral I, Rodrigo MP, Kloppe P, Rodríguez AI, González ML, Ariño D, Orozco D, Buitrago F, Pepió JM, Borrás I; PREseAP study research team. Brotons C, et al. Rev Esp Cardiol. 2011 Jan;64(1):13-20. doi: 10.1016/j.recesp.2010.07.005. Epub 2010 Dec 30. Rev Esp Cardiol. 2011. PMID: 21194823 Free article. Clinical Trial.