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SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis.
Wendisch D, Dietrich O, Mari T, von Stillfried S, Ibarra IL, Mittermaier M, Mache C, Chua RL, Knoll R, Timm S, Brumhard S, Krammer T, Zauber H, Hiller AL, Pascual-Reguant A, Mothes R, Bülow RD, Schulze J, Leipold AM, Djudjaj S, Erhard F, Geffers R, Pott F, Kazmierski J, Radke J, Pergantis P, Baßler K, Conrad C, Aschenbrenner AC, Sawitzki B, Landthaler M, Wyler E, Horst D; Deutsche COVID-19 OMICS Initiative (DeCOI); Hippenstiel S, Hocke A, Heppner FL, Uhrig A, Garcia C, Machleidt F, Herold S, Elezkurtaj S, Thibeault C, Witzenrath M, Cochain C, Suttorp N, Drosten C, Goffinet C, Kurth F, Schultze JL, Radbruch H, Ochs M, Eils R, Müller-Redetzky H, Hauser AE, Luecken MD, Theis FJ, Conrad C, Wolff T, Boor P, Selbach M, Saliba AE, Sander LE. Wendisch D, et al. Among authors: herold s. Cell. 2021 Dec 22;184(26):6243-6261.e27. doi: 10.1016/j.cell.2021.11.033. Epub 2021 Nov 27. Cell. 2021. PMID: 34914922 Free PMC article.
Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs.
Koppe U, Högner K, Doehn JM, Müller HC, Witzenrath M, Gutbier B, Bauer S, Pribyl T, Hammerschmidt S, Lohmeyer J, Suttorp N, Herold S, Opitz B. Koppe U, et al. Among authors: herold s. J Immunol. 2012 Jan 15;188(2):811-7. doi: 10.4049/jimmunol.1004143. Epub 2011 Dec 12. J Immunol. 2012. PMID: 22156592
Macrophage-expressed IFN-β contributes to apoptotic alveolar epithelial cell injury in severe influenza virus pneumonia.
Högner K, Wolff T, Pleschka S, Plog S, Gruber AD, Kalinke U, Walmrath HD, Bodner J, Gattenlöhner S, Lewe-Schlosser P, Matrosovich M, Seeger W, Lohmeyer J, Herold S. Högner K, et al. Among authors: herold s. PLoS Pathog. 2013 Feb;9(2):e1003188. doi: 10.1371/journal.ppat.1003188. Epub 2013 Feb 28. PLoS Pathog. 2013. PMID: 23468627 Free PMC article.
IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid.
Naujoks J, Tabeling C, Dill BD, Hoffmann C, Brown AS, Kunze M, Kempa S, Peter A, Mollenkopf HJ, Dorhoi A, Kershaw O, Gruber AD, Sander LE, Witzenrath M, Herold S, Nerlich A, Hocke AC, van Driel I, Suttorp N, Bedoui S, Hilbi H, Trost M, Opitz B. Naujoks J, et al. Among authors: herold s. PLoS Pathog. 2016 Feb 1;12(2):e1005408. doi: 10.1371/journal.ppat.1005408. eCollection 2016 Feb. PLoS Pathog. 2016. PMID: 26829557 Free PMC article.
Influenza A Virus Virulence Depends on Two Amino Acids in the N-Terminal Domain of Its NS1 Protein To Facilitate Inhibition of the RNA-Dependent Protein Kinase PKR.
Schierhorn KL, Jolmes F, Bespalowa J, Saenger S, Peteranderl C, Dzieciolowski J, Mielke M, Budt M, Pleschka S, Herrmann A, Herold S, Wolff T. Schierhorn KL, et al. Among authors: herold s. J Virol. 2017 Apr 28;91(10):e00198-17. doi: 10.1128/JVI.00198-17. Print 2017 May 15. J Virol. 2017. PMID: 28250123 Free PMC article.
Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia.
Dietert K, Gutbier B, Wienhold SM, Reppe K, Jiang X, Yao L, Chaput C, Naujoks J, Brack M, Kupke A, Peteranderl C, Becker S, von Lachner C, Baal N, Slevogt H, Hocke AC, Witzenrath M, Opitz B, Herold S, Hackstein H, Sander LE, Suttorp N, Gruber AD. Dietert K, et al. Among authors: herold s. PLoS One. 2017 Nov 20;12(11):e0188251. doi: 10.1371/journal.pone.0188251. eCollection 2017. PLoS One. 2017. PMID: 29155867 Free PMC article.
Digital Image Analyses on Whole-Lung Slides in Mouse Models of Acute Pneumonia.
Dietert K, Nouailles G, Gutbier B, Reppe K, Berger S, Jiang X, Schauer AE, Hocke AC, Herold S, Slevogt H, Witzenrath M, Suttorp N, Gruber AD. Dietert K, et al. Among authors: herold s. Am J Respir Cell Mol Biol. 2018 Apr;58(4):440-448. doi: 10.1165/rcmb.2017-0337MA. Am J Respir Cell Mol Biol. 2018. PMID: 29361238
Influenza A Virus Infection Induces Apical Redistribution of Na+, K+-ATPase in Lung Epithelial Cells In Vitro and In Vivo.
Peteranderl C, Kuznetsova I, Schulze J, Hardt M, Lecuona E, Sznajder JI, Vadász I, Morty RE, Pleschka S, Wolff T, Herold S. Peteranderl C, et al. Among authors: herold s. Am J Respir Cell Mol Biol. 2019 Sep;61(3):395-398. doi: 10.1165/rcmb.2019-0096LE. Am J Respir Cell Mol Biol. 2019. PMID: 31469298 Free PMC article. No abstract available.
352 results