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c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity.
Serna R, Ramrakhiani A, Hernandez JC, Chen CL, Nakagawa C, Machida T, Ray RB, Zhan X, Tahara SM, Machida K. Serna R, et al. Among authors: hernandez jc. iScience. 2022 Apr 29;25(6):104325. doi: 10.1016/j.isci.2022.104325. eCollection 2022 Jun 17. iScience. 2022. PMID: 35601917 Free PMC article.
NOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells.
Choi HY, Zhu Y, Zhao X, Mehta S, Hernandez JC, Lee JJ, Kou Y, Machida R, Giacca M, Del Sal G, Ray R, Eoh H, Tahara SM, Chen L, Tsukamoto H, Machida K. Choi HY, et al. Among authors: hernandez jc. Exp Mol Med. 2024 Feb;56(2):461-477. doi: 10.1038/s12276-024-01174-6. Epub 2024 Feb 27. Exp Mol Med. 2024. PMID: 38409448 Free PMC article.
217 results