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The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver.
Mederacke I, Filliol A, Affo S, Nair A, Hernandez C, Sun Q, Hamberger F, Brundu F, Chen Y, Ravichandra A, Huebener P, Anke H, Shi H, Martínez García de la Torre RA, Smith JR, Henderson NC, Vondran FWR, Rothlin CV, Baehre H, Tabas I, Sancho-Bru P, Schwabe RF. Mederacke I, et al. Among authors: hernandez c. Sci Transl Med. 2022 Apr 6;14(639):eabe5795. doi: 10.1126/scitranslmed.abe5795. Epub 2022 Apr 6. Sci Transl Med. 2022. PMID: 35385339 Free PMC article.
HMGB1 and injury amplification.
Huebener P, Hernandez C, Schwabe RF. Huebener P, et al. Among authors: hernandez c. Oncotarget. 2015 Sep 15;6(27):23048-9. doi: 10.18632/oncotarget.5243. Oncotarget. 2015. PMID: 26309086 Free PMC article. No abstract available.
The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis.
Huebener P, Pradere JP, Hernandez C, Gwak GY, Caviglia JM, Mu X, Loike JD, Jenkins RE, Antoine DJ, Schwabe RF. Huebener P, et al. Among authors: hernandez c. J Clin Invest. 2019 Mar 4;130(4):1802. doi: 10.1172/JCI126975. eCollection 2019 Mar 4. J Clin Invest. 2019. PMID: 30829651 Free PMC article. No abstract available.
The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis.
Huebener P, Pradere JP, Hernandez C, Gwak GY, Caviglia JM, Mu X, Loike JD, Jenkins RE, Antoine DJ, Schwabe RF. Huebener P, et al. Among authors: hernandez c. J Clin Invest. 2019 Mar 4;130(4):1802. doi: 10.1172/JCI126976. eCollection 2019 Mar 4. J Clin Invest. 2019. PMID: 30829652 Free PMC article. No abstract available.
2,510 results