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A partial agonist of PPARγ prevents paclitaxel-induced peripheral neuropathy in mice, by inhibiting neuroinflammation.
Benvenutti L, Wolff FR, Corrêa TP, Melato J, Goldoni FC, De Faveri R, Patel YBK, de Souza JA, Grockoski HA, Nilz PM, Bombardelli CL, Remor AP, Varela KG, Costa NTC, Hernandes MZ, Lacerda MG, Rodrigues KD, Milton FA, Neves FAR, Pereira MES, Kormann Imianowsky EC, de Campos Buzzi F, Brunaldi Marutani VH, Stoeberl LC, Correa R, Eller S, de Oliveira TF, Gonçalves TBP, da Silva RC, Passos GF, da Costa R, Santin JR, Quintão NLM. Benvenutti L, et al. Among authors: hernandes mz. Br J Pharmacol. 2024 Apr;181(7):1128-1149. doi: 10.1111/bph.16244. Epub 2023 Dec 1. Br J Pharmacol. 2024. PMID: 37721089
Quercetin as an inhibitor of snake venom secretory phospholipase A2.
Cotrim CA, de Oliveira SC, Diz Filho EB, Fonseca FV, Baldissera L Jr, Antunes E, Ximenes RM, Monteiro HS, Rabello MM, Hernandes MZ, de Oliveira Toyama D, Toyama MH. Cotrim CA, et al. Among authors: hernandes mz. Chem Biol Interact. 2011 Jan 15;189(1-2):9-16. doi: 10.1016/j.cbi.2010.10.016. Epub 2010 Nov 4. Chem Biol Interact. 2011. PMID: 21056032 Free article.
Discovery of phthalimides as immunomodulatory and antitumor drug prototypes.
Pessoa C, Ferreira PM, Lotufo LV, de Moraes MO, Cavalcanti SM, Coêlho LC, Hernandes MZ, Leite AC, De Simone CA, Costa VM, Souza VM. Pessoa C, et al. Among authors: hernandes mz. ChemMedChem. 2010 Apr 6;5(4):523-8. doi: 10.1002/cmdc.200900525. ChemMedChem. 2010. PMID: 20112332 No abstract available.
Design, synthesis and structure-activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities.
Cardoso MV, Moreira DR, Oliveira Filho GB, Cavalcanti SM, Coelho LC, Espíndola JW, Gonzalez LR, Rabello MM, Hernandes MZ, Ferreira PM, Pessoa C, Alberto de Simone C, Guimarães ET, Soares MB, Leite AC. Cardoso MV, et al. Among authors: hernandes mz. Eur J Med Chem. 2015;96:491-503. doi: 10.1016/j.ejmech.2015.04.041. Epub 2015 Apr 20. Eur J Med Chem. 2015. PMID: 25942060
Synthesis, docking, and in vitro activity of thiosemicarbazones, aminoacyl-thiosemicarbazides and acyl-thiazolidones against Trypanosoma cruzi.
Leite AC, de Lima RS, Moreira DR, Cardoso MV, Gouveia de Brito AC, Farias Dos Santos LM, Hernandes MZ, Kiperstok AC, de Lima RS, Soares MB. Leite AC, et al. Among authors: hernandes mz. Bioorg Med Chem. 2006 Jun 1;14(11):3749-57. doi: 10.1016/j.bmc.2006.01.034. Epub 2006 Feb 3. Bioorg Med Chem. 2006. PMID: 16458521
Harpalycin 2 inhibits the enzymatic and platelet aggregation activities of PrTX-III, a D49 phospholipase A2 from Bothrops pirajai venom.
Ximenes RM, Alves RS, Pereira TP, Araújo RM, Silveira ER, Rabello MM, Hernandes MZ, Soares VC, Bristot D, Pires CL, Toyama DO, Gaeta HH, Monteiro HS, Toyama MH. Ximenes RM, et al. Among authors: hernandes mz. BMC Complement Altern Med. 2012 Aug 27;12:139. doi: 10.1186/1472-6882-12-139. BMC Complement Altern Med. 2012. PMID: 22925825 Free PMC article.
Isolation, homology modeling and renal effects of a C-type natriuretic peptide from the venom of the Brazilian yellow scorpion (Tityus serrulatus).
Alves RS, Ximenes RM, Jorge AR, Nascimento NR, Martins RD, Rabello MM, Hernandes MZ, Toyama DO, Toyama MH, Martins AM, Havt A, Monteiro HS. Alves RS, et al. Among authors: hernandes mz. Toxicon. 2013 Nov;74:19-26. doi: 10.1016/j.toxicon.2013.07.016. Epub 2013 Jul 31. Toxicon. 2013. PMID: 23911732 Free article.
46 results