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A partial agonist of PPARγ prevents paclitaxel-induced peripheral neuropathy in mice, by inhibiting neuroinflammation.
Benvenutti L, Wolff FR, Corrêa TP, Melato J, Goldoni FC, De Faveri R, Patel YBK, de Souza JA, Grockoski HA, Nilz PM, Bombardelli CL, Remor AP, Varela KG, Costa NTC, Hernandes MZ, Lacerda MG, Rodrigues KD, Milton FA, Neves FAR, Pereira MES, Kormann Imianowsky EC, de Campos Buzzi F, Brunaldi Marutani VH, Stoeberl LC, Correa R, Eller S, de Oliveira TF, Gonçalves TBP, da Silva RC, Passos GF, da Costa R, Santin JR, Quintão NLM. Benvenutti L, et al. Among authors: hernandes mz. Br J Pharmacol. 2024 Apr;181(7):1128-1149. doi: 10.1111/bph.16244. Epub 2023 Dec 1. Br J Pharmacol. 2024. PMID: 37721089
Streptomyces hygroscopicus UFPEDA 3370: A valuable source of the potent cytotoxic agent nigericin and its evaluation against human colorectal cancer cells.
Garcia-Princival IMR, Princival JL, Dias da Silva E, de Arruda Lima SM, Carregosa JC, Wisniewski A Jr, de Lucena CCO, Halwass F, Alves Franca JA, Ferreira LFGR, Hernandes MZ, Saraiva KLA, Peixoto CA, Baratte B, Robert T, Bach S, Gomes DC, Guedes Paiva PM, Marchand P, Rodrigues MDD, Gonçalves da Silva T. Garcia-Princival IMR, et al. Among authors: hernandes mz. Chem Biol Interact. 2021 Jan 5;333:109316. doi: 10.1016/j.cbi.2020.109316. Epub 2020 Dec 4. Chem Biol Interact. 2021. PMID: 33285127
In vitro bioevaluation and docking study of dihydrosphingosine and ethambutol analogues against sensitive and multi-drug resistant Mycobacterium tuberculosis.
Linhares LA, Dos Santos Peixoto A, Correia de Sousa LA, Lucena Laet JP, da Silva Santos AC, Alves Pereira VR, Carneiro Neves MM, Ferreira LFGR, Hernandes MZ, de la Vega J, Pereira-Neves A, San Feliciano A, Olmo ED, Schindler HC, Montenegro LML. Linhares LA, et al. Among authors: hernandes mz. Eur J Med Chem. 2023 Oct 5;258:115579. doi: 10.1016/j.ejmech.2023.115579. Epub 2023 Jun 19. Eur J Med Chem. 2023. PMID: 37399709
Trypanosoma cruzi killing and immune response boosting by novel phenoxyhydrazine-thiazole against Chagas disease.
Cristovão-Silva AC, Brelaz-de-Castro MCA, Dionisio da Silva E, Leite ACL, Santiago LBAA, Conceição JMD, da Silva Tiburcio R, de Santana DP, Bedor DCG, de Carvalho BÍV, Ferreira LFGR, de Freitas E Silva R, Alves Pereira VR, Hernandes MZ. Cristovão-Silva AC, et al. Among authors: hernandes mz. Exp Parasitol. 2024 Apr 7;261:108749. doi: 10.1016/j.exppara.2024.108749. Online ahead of print. Exp Parasitol. 2024. PMID: 38593864
Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity.
Moreira DR, Leite AC, Cardoso MV, Srivastava RM, Hernandes MZ, Rabello MM, da Cruz LF, Ferreira RS, de Simone CA, Meira CS, Guimaraes ET, da Silva AC, dos Santos TA, Pereira VR, Soares MB. Moreira DR, et al. Among authors: hernandes mz. ChemMedChem. 2014 Jan;9(1):177-88. doi: 10.1002/cmdc.201300354. Epub 2013 Nov 7. ChemMedChem. 2014. PMID: 24203393
46 results