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Page 1
Chagas Disease Treatment and Rational Drug Discovery: A Challenge That Remains.
Silva ACC, Brelaz-de-Castro MCA, Leite ACL, Pereira VRA, Hernandes MZ. Silva ACC, et al. Among authors: hernandes mz. Front Pharmacol. 2019 Aug 2;10:873. doi: 10.3389/fphar.2019.00873. eCollection 2019. Front Pharmacol. 2019. PMID: 31427977 Free PMC article. No abstract available.
Synthesis, docking, and in vitro activity of thiosemicarbazones, aminoacyl-thiosemicarbazides and acyl-thiazolidones against Trypanosoma cruzi.
Leite AC, de Lima RS, Moreira DR, Cardoso MV, Gouveia de Brito AC, Farias Dos Santos LM, Hernandes MZ, Kiperstok AC, de Lima RS, Soares MB. Leite AC, et al. Among authors: hernandes mz. Bioorg Med Chem. 2006 Jun 1;14(11):3749-57. doi: 10.1016/j.bmc.2006.01.034. Epub 2006 Feb 3. Bioorg Med Chem. 2006. PMID: 16458521
Structural investigation of anti-Trypanosoma cruzi 2-iminothiazolidin-4-ones allows the identification of agents with efficacy in infected mice.
Moreira DR, Costa SP, Hernandes MZ, Rabello MM, de Oliveira Filho GB, de Melo CM, da Rocha LF, de Simone CA, Ferreira RS, Fradico JR, Meira CS, Guimarães ET, Srivastava RM, Pereira VR, Soares MB, Leite AC. Moreira DR, et al. Among authors: hernandes mz. J Med Chem. 2012 Dec 27;55(24):10918-36. doi: 10.1021/jm301518v. Epub 2012 Dec 7. J Med Chem. 2012. PMID: 23167554
Sulfonamide-metal complexes endowed with potent anti-Trypanosoma cruzi activity.
Chohan ZH, Hernandes MZ, Sensato FR, Moreira DR, Pereira VR, Neves JK, de Oliveira AP, de Oliveira BC, Leite AC. Chohan ZH, et al. Among authors: hernandes mz. J Enzyme Inhib Med Chem. 2014 Apr;29(2):230-6. doi: 10.3109/14756366.2013.766608. Epub 2013 Feb 25. J Enzyme Inhib Med Chem. 2014. PMID: 23432595
Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity.
Moreira DR, Leite AC, Cardoso MV, Srivastava RM, Hernandes MZ, Rabello MM, da Cruz LF, Ferreira RS, de Simone CA, Meira CS, Guimaraes ET, da Silva AC, dos Santos TA, Pereira VR, Soares MB. Moreira DR, et al. Among authors: hernandes mz. ChemMedChem. 2014 Jan;9(1):177-88. doi: 10.1002/cmdc.201300354. Epub 2013 Nov 7. ChemMedChem. 2014. PMID: 24203393
2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: structural design, synthesis and pharmacological evaluation.
Cardoso MV, de Siqueira LR, da Silva EB, Costa LB, Hernandes MZ, Rabello MM, Ferreira RS, da Cruz LF, Moreira DR, Pereira VR, de Castro MC, Bernhardt PV, Leite AC. Cardoso MV, et al. Among authors: hernandes mz. Eur J Med Chem. 2014 Oct 30;86:48-59. doi: 10.1016/j.ejmech.2014.08.012. Epub 2014 Aug 6. Eur J Med Chem. 2014. PMID: 25147146
Design, synthesis and structure-activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities.
Cardoso MV, Moreira DR, Oliveira Filho GB, Cavalcanti SM, Coelho LC, Espíndola JW, Gonzalez LR, Rabello MM, Hernandes MZ, Ferreira PM, Pessoa C, Alberto de Simone C, Guimarães ET, Soares MB, Leite AC. Cardoso MV, et al. Among authors: hernandes mz. Eur J Med Chem. 2015;96:491-503. doi: 10.1016/j.ejmech.2015.04.041. Epub 2015 Apr 20. Eur J Med Chem. 2015. PMID: 25942060
46 results