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CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition.
Quijada-Álamo M, Hernández-Sánchez M, Alonso-Pérez V, Rodríguez-Vicente AE, García-Tuñón I, Martín-Izquierdo M, Hernández-Sánchez JM, Herrero AB, Bastida JM, San Segundo L, Gruber M, García JL, Yin S, Ten Hacken E, Benito R, Ordóñez JL, Wu CJ, Hernández-Rivas JM. Quijada-Álamo M, et al. Leukemia. 2020 Jun;34(6):1599-1612. doi: 10.1038/s41375-020-0714-3. Epub 2020 Jan 23. Leukemia. 2020. PMID: 31974435 Free PMC article.
Detection of translocations affecting the BCL6 locus in B cell non-Hodgkin's lymphoma by interphase fluorescence in situ hybridization.
Sanchez-Izquierdo D, Siebert R, Harder L, Marugan I, Gozzetti A, Price HP, Gesk S, Hernandez-Rivas JM, Benet I, Solé F, Sonoki T, Le Beau MM, Schlegelberger B, Dyer MJ, Garcia-Conde J, Martinez-Climent JA. Sanchez-Izquierdo D, et al. Leukemia. 2001 Sep;15(9):1475-84. doi: 10.1038/sj.leu.2402207. Leukemia. 2001. PMID: 11516111
Prognostic impact of the number of methylated genes in myelodysplastic syndromes and acute myeloid leukemias treated with azacytidine.
Abáigar M, Ramos F, Benito R, Díez-Campelo M, Sánchez-del-Real J, Hermosín L, Rodríguez JN, Aguilar C, Recio I, Alonso JM, de las Heras N, Megido M, Fuertes M, del Cañizo MC, Hernández-Rivas JM. Abáigar M, et al. Ann Hematol. 2013 Nov;92(11):1543-52. doi: 10.1007/s00277-013-1799-9. Epub 2013 Jun 6. Ann Hematol. 2013. PMID: 23740492
A high proportion of cells carrying trisomy 12 is associated with a worse outcome in patients with chronic lymphocytic leukemia.
González-Gascón Y Marín I, Hernández-Sánchez M, Rodríguez-Vicente AE, Sanzo C, Aventín A, Puiggros A, Collado R, Heras C, Muñoz C, Delgado J, Ortega M, González MT, Marugán I, de la Fuente I, Recio I, Bosch F, Espinet B, González M, Hernández-Rivas JM, Hernández JÁ; Grupo Español de Leucemia Linfática Crónica (GELLC); Grupo Cooperativo Español de Citogenética Hematológica (GCECGH). González-Gascón Y Marín I, et al. Hematol Oncol. 2016 Jun;34(2):84-92. doi: 10.1002/hon.2196. Epub 2015 Feb 17. Hematol Oncol. 2016. PMID: 25689772
MicroRNA-223 is a novel negative regulator of HSP90B1 in CLL.
Rodríguez-Vicente AE, Quwaider D, Benito R, Misiewicz-Krzeminska I, Hernández-Sánchez M, de Coca AG, Fisac R, Alonso JM, Zato C, de Paz JF, García JL, Sarasquete ME, Hernández JÁ, Corchado JM, González M, Gutiérrez NC, Hernández-Rivas JM. Rodríguez-Vicente AE, et al. BMC Cancer. 2015 Apr 8;15:238. doi: 10.1186/s12885-015-1212-2. BMC Cancer. 2015. PMID: 25880332 Free PMC article.
A Low Frequency of Losses in 11q Chromosome Is Associated with Better Outcome and Lower Rate of Genomic Mutations in Patients with Chronic Lymphocytic Leukemia.
Hernández JÁ, Hernández-Sánchez M, Rodríguez-Vicente AE, Grossmann V, Collado R, Heras C, Puiggros A, Martín AÁ, Puig N, Benito R, Robledo C, Delgado J, González T, Queizán JA, Galende J, de la Fuente I, Martín-Núñez G, Alonso JM, Abrisqueta P, Luño E, Marugán I, González-Gascón I, Bosch F, Kohlmann A, González M, Espinet B, Hernández-Rivas JM; Grupo Cooperativo Español de Citogenética Hematológica (GCECGH) and Grupo Español de Leucemia Linfática Crónica (GELLC). Hernández JÁ, et al. PLoS One. 2015 Dec 2;10(11):e0143073. doi: 10.1371/journal.pone.0143073. eCollection 2015. PLoS One. 2015. PMID: 26630574 Free PMC article.
MiRNA expression profile of chronic lymphocytic leukemia patients with 13q deletion.
Hernández-Sánchez M, Rodríguez-Vicente AE, Hernández JÁ, Lumbreras E, Sarasquete ME, Martín AÁ, Benito R, Vicente-Gutiérrez C, Robledo C, Heras Nde L, Rodríguez JN, Alcoceba M, Coca AG, Aguilar C, González M, Hernández-Rivas JM. Hernández-Sánchez M, et al. Leuk Res. 2016 Jul;46:30-6. doi: 10.1016/j.leukres.2016.04.008. Epub 2016 Apr 12. Leuk Res. 2016. PMID: 27111859
Hyperdiploidy as a rare event that accompanies poor prognosis markers in CLL.
González-Gascón Y Marín I, Martín AÁ, Hernández-Sanchez M, Robledo C, Hermosín ML, de Las Heras N, Lacalle L, Galende J, de Arriba F, Rodríguez-Vicente AE, Hernández JÁ, Hernández-Rivas JM. González-Gascón Y Marín I, et al. Eur J Haematol. 2017 Feb;98(2):142-148. doi: 10.1111/ejh.12812. Epub 2016 Oct 12. Eur J Haematol. 2017. PMID: 27717146
177 results