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Improved yield, stability, and cleavage reaction of a novel tobacco etch virus protease mutant.
Enríquez-Flores S, De la Mora-De la Mora JI, Flores-López LA, Cabrera N, Fernández-Lainez C, Hernández-Alcántara G, Guerrero-Beltrán CE, López-Velázquez G, García-Torres I. Enríquez-Flores S, et al. Among authors: hernandez alcantara g. Appl Microbiol Biotechnol. 2022 Feb;106(4):1475-1492. doi: 10.1007/s00253-022-11786-5. Epub 2022 Jan 29. Appl Microbiol Biotechnol. 2022. PMID: 35092453 Review.
The stability of G6PD is affected by mutations with different clinical phenotypes.
Gómez-Manzo S, Terrón-Hernández J, De la Mora-De la Mora I, González-Valdez A, Marcial-Quino J, García-Torres I, Vanoye-Carlo A, López-Velázquez G, Hernández-Alcántara G, Oria-Hernández J, Reyes-Vivas H, Enríquez-Flores S. Gómez-Manzo S, et al. Among authors: hernandez alcantara g. Int J Mol Sci. 2014 Nov 17;15(11):21179-201. doi: 10.3390/ijms151121179. Int J Mol Sci. 2014. PMID: 25407525 Free PMC article.
Structural and functional perturbation of Giardia lamblia triosephosphate isomerase by modification of a non-catalytic, non-conserved region.
Hernández-Alcántara G, Torres-Larios A, Enríquez-Flores S, García-Torres I, Castillo-Villanueva A, Méndez ST, de la Mora-de la Mora I, Gómez-Manzo S, Torres-Arroyo A, López-Velázquez G, Reyes-Vivas H, Oria-Hernández J. Hernández-Alcántara G, et al. PLoS One. 2013 Jul 22;8(7):e69031. doi: 10.1371/journal.pone.0069031. Print 2013. PLoS One. 2013. PMID: 23894402 Free PMC article.
First characterization of a microsporidial triosephosphate isomerase and the biochemical mechanisms of its inactivation to propose a new druggable target.
García-Torres I, De la Mora-De la Mora I, Hernández-Alcántara G, Molina-Ortiz D, Caballero-Salazar S, Olivos-García A, Nava G, López-Velázquez G, Enríquez-Flores S. García-Torres I, et al. Among authors: hernandez alcantara g. Sci Rep. 2018 Jun 5;8(1):8591. doi: 10.1038/s41598-018-26845-z. Sci Rep. 2018. PMID: 29872223 Free PMC article.
Determining the molecular mechanism of inactivation by chemical modification of triosephosphate isomerase from the human parasite Giardia lamblia: a study for antiparasitic drug design.
Enríquez-Flores S, Rodríguez-Romero A, Hernández-Alcántara G, Oria-Hernández J, Gutiérrez-Castrellón P, Pérez-Hernández G, de la Mora-de la Mora I, Castillo-Villanueva A, García-Torres I, Méndez ST, Gómez-Manzo S, Torres-Arroyo A, López-Velázquez G, Reyes-Vivas H. Enríquez-Flores S, et al. Proteins. 2011 Sep;79(9):2711-24. doi: 10.1002/prot.23100. Epub 2011 Jul 22. Proteins. 2011. PMID: 21786322
Giardial triosephosphate isomerase as possible target of the cytotoxic effect of omeprazole in Giardia lamblia.
Reyes-Vivas H, de la Mora-de la Mora I, Castillo-Villanueva A, Yépez-Mulia L, Hernández-Alcántara G, Figueroa-Salazar R, García-Torres I, Gómez-Manzo S, Méndez ST, Vanoye-Carlo A, Marcial-Quino J, Torres-Arroyo A, Oria-Hernández J, Gutiérrez-Castrellón P, Enríquez-Flores S, López-Velázquez G. Reyes-Vivas H, et al. Among authors: hernandez alcantara g. Antimicrob Agents Chemother. 2014 Dec;58(12):7072-82. doi: 10.1128/AAC.02900-14. Epub 2014 Sep 15. Antimicrob Agents Chemother. 2014. PMID: 25223993 Free PMC article.
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