Herms A - Search Results

1

Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium.

Colom B, Alcolea MP, Piedrafita G, Hall MWJ, Wabik A, Dentro SC, Fowler JC, Herms A, King C, Ong SH, Sood RK, Gerstung M, Martincorena I, Hall BA, Jones PH. Colom B, et al. Among authors: herms a. Nat Genet. 2020 Jun;52(6):604-614. doi: 10.1038/s41588-020-0624-3. Epub 2020 May 18. Nat Genet. 2020. PMID: 32424351 Free PMC article.

2

Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation.

Fernandez-Antoran D, Piedrafita G, Murai K, Ong SH, Herms A, Frezza C, Jones PH. Fernandez-Antoran D, et al. Among authors: herms a. Cell Stem Cell. 2019 Sep 5;25(3):329-341.e6. doi: 10.1016/j.stem.2019.06.011. Epub 2019 Jul 18. Cell Stem Cell. 2019. PMID: 31327664 Free PMC article.

3

A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice.

Piedrafita G, Kostiou V, Wabik A, Colom B, Fernandez-Antoran D, Herms A, Murai K, Hall BA, Jones PH. Piedrafita G, et al. Among authors: herms a. Nat Commun. 2020 Mar 18;11(1):1429. doi: 10.1038/s41467-020-15258-0. Nat Commun. 2020. PMID: 32188860 Free PMC article.

4

Mutant clones in normal epithelium outcompete and eliminate emerging tumours.

Colom B, Herms A, Hall MWJ, Dentro SC, King C, Sood RK, Alcolea MP, Piedrafita G, Fernandez-Antoran D, Ong SH, Fowler JC, Mahbubani KT, Saeb-Parsy K, Gerstung M, Hall BA, Jones PH. Colom B, et al. Among authors: herms a. Nature. 2021 Oct;598(7881):510-514. doi: 10.1038/s41586-021-03965-7. Epub 2021 Oct 13. Nature. 2021. PMID: 34646013 Free PMC article.

5

p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition.

Murai K, Dentro S, Ong SH, Sood R, Fernandez-Antoran D, Herms A, Kostiou V, Abnizova I, Hall BA, Gerstung M, Jones PH. Murai K, et al. Among authors: herms a. Nat Commun. 2022 Oct 20;13(1):6206. doi: 10.1038/s41467-022-33945-y. Nat Commun. 2022. PMID: 36266286 Free PMC article.

6

Splitting up differentiation and cell cycle exit.

Herms A, Jones PH. Herms A, et al. Nat Cell Biol. 2022 Dec;24(12):1687-1688. doi: 10.1038/s41556-022-01022-7. Nat Cell Biol. 2022. PMID: 36357620 No abstract available.

7

Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth.

Abby E, Dentro SC, Hall MWJ, Fowler JC, Ong SH, Sood R, Herms A, Piedrafita G, Abnizova I, Siebel CW, Gerstung M, Hall BA, Jones PH. Abby E, et al. Among authors: herms a. Nat Genet. 2023 Feb;55(2):232-245. doi: 10.1038/s41588-022-01280-z. Epub 2023 Jan 19. Nat Genet. 2023. PMID: 36658434 Free PMC article.

8

AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation.

Herms A, Bosch M, Reddy BJ, Schieber NL, Fajardo A, Rupérez C, Fernández-Vidal A, Ferguson C, Rentero C, Tebar F, Enrich C, Parton RG, Gross SP, Pol A. Herms A, et al. Nat Commun. 2015 May 27;6:7176. doi: 10.1038/ncomms8176. Nat Commun. 2015. PMID: 26013497 Free PMC article.

9

Triton X-100 promotes a cholesterol-dependent condensation of the plasma membrane.

Ingelmo-Torres M, Gaus K, Herms A, González-Moreno E, Kassan A, Bosch M, Grewal T, Tebar F, Enrich C, Pol A. Ingelmo-Torres M, et al. Among authors: herms a. Biochem J. 2009 May 27;420(3):373-81. doi: 10.1042/BJ20090051. Biochem J. 2009. PMID: 19309310

10

Hydrophobic and basic domains target proteins to lipid droplets.

Ingelmo-Torres M, González-Moreno E, Kassan A, Hanzal-Bayer M, Tebar F, Herms A, Grewal T, Hancock JF, Enrich C, Bosch M, Gross SP, Parton RG, Pol A. Ingelmo-Torres M, et al. Among authors: herms a. Traffic. 2009 Dec;10(12):1785-801. doi: 10.1111/j.1600-0854.2009.00994.x. Epub 2009 Oct 5. Traffic. 2009. PMID: 19874557 Free PMC article.

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