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Chronic peroxisome proliferator-activated receptorβ/δ agonist GW0742 prevents hypertension, vascular inflammatory and oxidative status, and endothelial dysfunction in diet-induced obesity.
Toral M, Gómez-Guzmán M, Jiménez R, Romero M, Zarzuelo MJ, Utrilla MP, Hermenegildo C, Cogolludo Á, Pérez-Vizcaíno F, Gálvez J, Duarte J. Toral M, et al. Among authors: hermenegildo c. J Hypertens. 2015 Sep;33(9):1831-44. doi: 10.1097/HJH.0000000000000634. J Hypertens. 2015. PMID: 26147382
Trans- but not cis-resveratrol impairs angiotensin-II-mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated receptor-gamma upregulation.
Rius C, Abu-Taha M, Hermenegildo C, Piqueras L, Cerda-Nicolas JM, Issekutz AC, Estañ L, Cortijo J, Morcillo EJ, Orallo F, Sanz MJ. Rius C, et al. Among authors: hermenegildo c. J Immunol. 2010 Sep 15;185(6):3718-27. doi: 10.4049/jimmunol.1001043. Epub 2010 Aug 13. J Immunol. 2010. PMID: 20709957
Estradiol, acting through estrogen receptor alpha, restores dimethylarginine dimethylaminohydrolase activity and nitric oxide production in oxLDL-treated human arterial endothelial cells.
Novella S, Laguna-Fernández A, Lázaro-Franco M, Sobrino A, Bueno-Betí C, Tarín JJ, Monsalve E, Sanchís J, Hermenegildo C. Novella S, et al. Among authors: hermenegildo c. Mol Cell Endocrinol. 2013 Jan 5;365(1):11-6. doi: 10.1016/j.mce.2012.08.020. Epub 2012 Sep 7. Mol Cell Endocrinol. 2013. PMID: 22982060 Free article.
Complete blockade of the vasorelaxant effects of angiotensin-(1-7) and bradykinin in murine microvessels by antagonists of the receptor Mas.
Peiró C, Vallejo S, Gembardt F, Palacios E, Novella S, Azcutia V, Rodríguez-Mañas L, Hermenegildo C, Sánchez-Ferrer CF, Walther T. Peiró C, et al. Among authors: hermenegildo c. J Physiol. 2013 May 1;591(9):2275-85. doi: 10.1113/jphysiol.2013.251413. Epub 2013 Mar 4. J Physiol. 2013. PMID: 23459756 Free PMC article.
Combined sub-optimal doses of rosuvastatin and bexarotene impair angiotensin II-induced arterial mononuclear cell adhesion through inhibition of Nox5 signaling pathways and increased RXR/PPARα and RXR/PPARγ interactions.
Escudero P, Martinez de Marañón A, Collado A, Gonzalez-Navarro H, Hermenegildo C, Peiró C, Piqueras L, Sanz MJ. Escudero P, et al. Among authors: hermenegildo c. Antioxid Redox Signal. 2015 Apr 10;22(11):901-20. doi: 10.1089/ars.2014.5969. Epub 2015 Mar 9. Antioxid Redox Signal. 2015. PMID: 25602514 Free PMC article.
117 results