Hermanns HM - Search Results

1

Principles of interleukin (IL)-6-type cytokine signalling and its regulation.

Heinrich PC, Behrmann I, Haan S, Hermanns HM, Müller-Newen G, Schaper F. Heinrich PC, et al. Among authors: hermanns hm. Biochem J. 2003 Aug 15;374(Pt 1):1-20. doi: 10.1042/BJ20030407. Biochem J. 2003. PMID: 12773095 Free PMC article. Review.

2

Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation.

Radtke S, Wüller S, Yang XP, Lippok BE, Mütze B, Mais C, de Leur HS, Bode JG, Gaestel M, Heinrich PC, Behrmann I, Schaper F, Hermanns HM. Radtke S, et al. Among authors: hermanns hm. J Cell Sci. 2010 Mar 15;123(Pt 6):947-59. doi: 10.1242/jcs.065326. J Cell Sci. 2010. PMID: 20200229 Free article.

3

A single amino acid substitution (Trp(666)-->Ala) in the interbox1/2 region of the interleukin-6 signal transducer gp130 abrogates binding of JAK1, and dominantly impairs signal transduction.

Haan C, Hermanns HM, Heinrich PC, Behrmann I. Haan C, et al. Among authors: hermanns hm. Biochem J. 2000 Jul 1;349(Pt 1):261-6. doi: 10.1042/0264-6021:3490261. Biochem J. 2000. PMID: 10861237 Free PMC article.

4

Non-redundant signal transduction of interleukin-6-type cytokines. The adapter protein Shc is specifically recruited to rhe oncostatin M receptor.

Hermanns HM, Radtke S, Schaper F, Heinrich PC, Behrmann I. Hermanns HM, et al. J Biol Chem. 2000 Dec 29;275(52):40742-8. doi: 10.1074/jbc.M005408200. J Biol Chem. 2000. PMID: 11016927 Free article.

5

Novel role of Janus kinase 1 in the regulation of oncostatin M receptor surface expression.

Radtke S, Hermanns HM, Haan C, Schmitz-Van De Leur H, Gascan H, Heinrich PC, Behrmann I. Radtke S, et al. Among authors: hermanns hm. J Biol Chem. 2002 Mar 29;277(13):11297-305. doi: 10.1074/jbc.M100822200. Epub 2002 Jan 10. J Biol Chem. 2002. PMID: 11786531 Free article.

6

Orientational constraints of the gp130 intracellular juxtamembrane domain for signaling.

Greiser JS, Stross C, Heinrich PC, Behrmann I, Hermanns HM. Greiser JS, et al. Among authors: hermanns hm. J Biol Chem. 2002 Jul 26;277(30):26959-65. doi: 10.1074/jbc.M204113200. Epub 2002 May 14. J Biol Chem. 2002. PMID: 12011064 Free article.

7

Characterization of the signaling capacities of the novel gp130-like cytokine receptor.

Dreuw A, Radtke S, Pflanz S, Lippok BE, Heinrich PC, Hermanns HM. Dreuw A, et al. Among authors: hermanns hm. J Biol Chem. 2004 Aug 20;279(34):36112-20. doi: 10.1074/jbc.M401122200. Epub 2004 Jun 11. J Biol Chem. 2004. PMID: 15194700 Free article.

8

The tyrosine 974 within the LIF-R-chain of the gp130/LIF-R heteromeric receptor complex mediates negative regulation of LIF signalling.

Clahsen T, Lehmann U, Stross C, Hermanns HM, Volkmer-Engert R, Schneider-Mergener J, Heinrich PC, Schaper F. Clahsen T, et al. Among authors: hermanns hm. Cell Signal. 2005 May;17(5):559-69. doi: 10.1016/j.cellsig.2004.09.016. Cell Signal. 2005. PMID: 15683731

9

The Jak1 SH2 domain does not fulfill a classical SH2 function in Jak/STAT signaling but plays a structural role for receptor interaction and up-regulation of receptor surface expression.

Radtke S, Haan S, Jörissen A, Hermanns HM, Diefenbach S, Smyczek T, Schmitz-Vandeleur H, Heinrich PC, Behrmann I, Haan C. Radtke S, et al. Among authors: hermanns hm. J Biol Chem. 2005 Jul 8;280(27):25760-8. doi: 10.1074/jbc.M500822200. Epub 2005 May 12. J Biol Chem. 2005. PMID: 15894543 Free article.

10

Oncostatin M-induced activation of stress-activated MAP kinases depends on tyrosine 861 in the OSM receptor and requires Jak1 but not Src kinases.

Böing I, Stross C, Radtke S, Lippok BE, Heinrich PC, Hermanns HM. Böing I, et al. Among authors: hermanns hm. Cell Signal. 2006 Jan;18(1):50-61. doi: 10.1016/j.cellsig.2005.03.015. Epub 2005 Jun 1. Cell Signal. 2006. PMID: 15935618

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