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p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway.
Fondevila MF, Novoa E, Gonzalez-Rellan MJ, Fernandez U, Heras V, Porteiro B, Parracho T, Dorta V, Riobello C, da Silva Lima N, Seoane S, Garcia-Vence M, Chantada-Vazquez MP, Bravo SB, Senra A, Leiva M, Marcos M, Sabio G, Perez-Fernandez R, Dieguez C, Prevot V, Schwaninger M, Woodhoo A, Martinez-Chantar ML, Schwabe R, Cubero FJ, Varela-Rey M, Crespo J, Iruzubieta P, Nogueiras R. Fondevila MF, et al. Among authors: heras v. Cell Rep Med. 2024 Feb 20;5(2):101401. doi: 10.1016/j.xcrm.2024.101401. Epub 2024 Feb 9. Cell Rep Med. 2024. PMID: 38340725 Free PMC article.
Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.
Gonzalez-Rellan MJ, Parracho T, Heras V, Rodriguez A, Fondevila MF, Novoa E, Lima N, Varela-Rey M, Senra A, Chantada-Vazquez MDP, Ameneiro C, Bernardo G, Fernandez-Ramos D, Lopitz-Otsoa F, Bilbao J, Guallar D, Fidalgo M, Bravo S, Dieguez C, Martinez-Chantar ML, Millet O, Mato JM, Schwaninger M, Prevot V, Crespo J, Frühbeck G, Iruzubieta P, Nogueiras R. Gonzalez-Rellan MJ, et al. Among authors: heras v. Mol Metab. 2023 Sep;75:101776. doi: 10.1016/j.molmet.2023.101776. Epub 2023 Jul 13. Mol Metab. 2023. PMID: 37453647 Free PMC article.
Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice.
Roa J, Ruiz-Cruz M, Ruiz-Pino F, Onieva R, Vazquez MJ, Sanchez-Tapia MJ, Ruiz-Rodriguez JM, Sobrino V, Barroso A, Heras V, Velasco I, Perdices-Lopez C, Ohlsson C, Avendaño MS, Prevot V, Poutanen M, Pinilla L, Gaytan F, Tena-Sempere M. Roa J, et al. Among authors: heras v. Nat Commun. 2022 Aug 9;13(1):4663. doi: 10.1038/s41467-022-32347-4. Nat Commun. 2022. PMID: 35945211 Free PMC article.
Prolonged breastfeeding protects from obesity by hypothalamic action of hepatic FGF21.
Pena-Leon V, Folgueira C, Barja-Fernández S, Pérez-Lois R, Da Silva Lima N, Martin M, Heras V, Martinez-Martinez S, Valero P, Iglesias C, Duquenne M, Al-Massadi O, Beiroa D, Souto Y, Fidalgo M, Sowmyalakshmi R, Guallar D, Cunarro J, Castelao C, Senra A, González-Saenz P, Vázquez-Cobela R, Leis R, Sabio G, Mueller-Fielitz H, Schwaninger M, López M, Tovar S, Casanueva FF, Valjent E, Diéguez C, Prevot V, Nogueiras R, Seoane LM. Pena-Leon V, et al. Among authors: heras v. Nat Metab. 2022 Jul;4(7):901-917. doi: 10.1038/s42255-022-00602-z. Epub 2022 Jul 25. Nat Metab. 2022. PMID: 35879461 Free PMC article.
Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway.
Romero-Picó A, Novelle MG, Al-Massadi O, Beiroa D, Tojo M, Heras V, Ruiz-Pino F, Senra A, López M, Blouet C, Tena-Sempere M, Nogueiras R, Diéguez C. Romero-Picó A, et al. Among authors: heras v. Int J Mol Sci. 2022 Mar 14;23(6):3118. doi: 10.3390/ijms23063118. Int J Mol Sci. 2022. PMID: 35328539 Free PMC article.
Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis.
Fondevila MF, Fernandez U, Heras V, Parracho T, Gonzalez-Rellan MJ, Novoa E, Porteiro B, Alonso C, Mayo R, da Silva Lima N, Iglesias C, Filliol AA, Senra A, Delgado TC, Woodhoo A, Herrero L, Serra D, Prevot V, Schwaninger M, López M, Dieguez C, Millet O, Mato JM, Cubero FJ, Varela-Rey M, Iruzubieta P, Crespo J, Martinez-Chantar ML, Schwabe RF, Nogueiras R. Fondevila MF, et al. Among authors: heras v. J Hepatol. 2022 Jul;77(1):15-28. doi: 10.1016/j.jhep.2022.02.003. Epub 2022 Feb 12. J Hepatol. 2022. PMID: 35167910 Free article.
Connecting nutritional deprivation and pubertal inhibition via GRK2-mediated repression of kisspeptin actions in GnRH neurons.
Perdices-Lopez C, Avendaño MS, Barroso A, Gaytán F, Ruiz-Pino F, Vázquez MJ, Leon S, Song YB, Sobrino V, Heras V, Romero-Ruiz A, Roa J, Mayor F Jr, Murga C, Pinilla L, Kaiser UB, Tena-Sempere M. Perdices-Lopez C, et al. Among authors: heras v. Metabolism. 2022 Apr;129:155141. doi: 10.1016/j.metabol.2022.155141. Epub 2022 Jan 22. Metabolism. 2022. PMID: 35074314 Free PMC article.
97 results