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Lentiviral vectors for inducible, transactivator-free advanced therapy medicinal products: Application to CAR-T cells.
Tristán-Manzano M, Maldonado-Pérez N, Justicia-Lirio P, Cortijo-Gutierréz M, Tristán-Ramos P, Blanco-Benítez C, Pavlovic K, Aguilar-González A, Muñoz P, Molina-Estevez FJ, Griesche V, Marchal JA, Heras SR, Benabdellah K, Martin F. Tristán-Manzano M, et al. Among authors: heras sr. Mol Ther Nucleic Acids. 2023 Mar 28;32:322-339. doi: 10.1016/j.omtn.2023.03.018. eCollection 2023 Jun 13. Mol Ther Nucleic Acids. 2023. PMID: 37125150 Free PMC article.
The tumor suppressor microRNA let-7 inhibits human LINE-1 retrotransposition.
Tristán-Ramos P, Rubio-Roldan A, Peris G, Sánchez L, Amador-Cubero S, Viollet S, Cristofari G, Heras SR. Tristán-Ramos P, et al. Among authors: heras sr. Nat Commun. 2020 Nov 11;11(1):5712. doi: 10.1038/s41467-020-19430-4. Nat Commun. 2020. PMID: 33177501 Free PMC article.
Synthesis and Characterization of Specific Reverse Transcriptase Inhibitors for Mammalian LINE-1 Retrotransposons.
Banuelos-Sanchez G, Sanchez L, Benitez-Guijarro M, Sanchez-Carnerero V, Salvador-Palomeque C, Tristan-Ramos P, Benkaddour-Boumzaouad M, Morell S, Garcia-Puche JL, Heras SR, Franco-Montalban F, Tamayo JA, Garcia-Perez JL. Banuelos-Sanchez G, et al. Among authors: heras sr. Cell Chem Biol. 2019 Aug 15;26(8):1095-1109.e14. doi: 10.1016/j.chembiol.2019.04.010. Epub 2019 May 30. Cell Chem Biol. 2019. PMID: 31155508 Free article.
Alu retrotransposons promote differentiation of human carcinoma cells through the aryl hydrocarbon receptor.
Morales-Hernández A, González-Rico FJ, Román AC, Rico-Leo E, Alvarez-Barrientos A, Sánchez L, Macia Á, Heras SR, García-Pérez JL, Merino JM, Fernández-Salguero PM. Morales-Hernández A, et al. Among authors: heras sr. Nucleic Acids Res. 2016 Jun 2;44(10):4665-83. doi: 10.1093/nar/gkw095. Epub 2016 Feb 15. Nucleic Acids Res. 2016. PMID: 26883630 Free PMC article.
LINE-1 Evasion of Epigenetic Repression in Humans.
Sanchez-Luque FJ, Kempen MHC, Gerdes P, Vargas-Landin DB, Richardson SR, Troskie RL, Jesuadian JS, Cheetham SW, Carreira PE, Salvador-Palomeque C, García-Cañadas M, Muñoz-Lopez M, Sanchez L, Lundberg M, Macia A, Heras SR, Brennan PM, Lister R, Garcia-Perez JL, Ewing AD, Faulkner GJ. Sanchez-Luque FJ, et al. Among authors: heras sr. Mol Cell. 2019 Aug 8;75(3):590-604.e12. doi: 10.1016/j.molcel.2019.05.024. Epub 2019 Jun 20. Mol Cell. 2019. PMID: 31230816 Free article.
The Microprocessor controls the activity of mammalian retrotransposons.
Heras SR, Macias S, Plass M, Fernandez N, Cano D, Eyras E, Garcia-Perez JL, Cáceres JF. Heras SR, et al. Nat Struct Mol Biol. 2013 Oct;20(10):1173-81. doi: 10.1038/nsmb.2658. Epub 2013 Sep 1. Nat Struct Mol Biol. 2013. PMID: 23995758 Free PMC article.
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