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Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer's disease via MFG-E8.
Tzioras M, Daniels MJD, Davies C, Baxter P, King D, McKay S, Varga B, Popovic K, Hernandez M, Stevenson AJ, Barrington J, Drinkwater E, Borella J, Holloway RK, Tulloch J, Moss J, Latta C, Kandasamy J, Sokol D, Smith C, Miron VE, Káradóttir RT, Hardingham GE, Henstridge CM, Brennan PM, McColl BW, Spires-Jones TL. Tzioras M, et al. Among authors: henstridge cm. Cell Rep Med. 2023 Sep 19;4(9):101175. doi: 10.1016/j.xcrm.2023.101175. Epub 2023 Aug 30. Cell Rep Med. 2023. PMID: 37652017 Free PMC article.
Modeling Alzheimer's disease brains in vitro.
Henstridge CM, Spires-Jones TL. Henstridge CM, et al. Nat Neurosci. 2018 Jul;21(7):899-900. doi: 10.1038/s41593-018-0177-2. Nat Neurosci. 2018. PMID: 29950667 No abstract available.
Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease.
Pickett EK, Herrmann AG, McQueen J, Abt K, Dando O, Tulloch J, Jain P, Dunnett S, Sohrabi S, Fjeldstad MP, Calkin W, Murison L, Jackson RJ, Tzioras M, Stevenson A, d'Orange M, Hooley M, Davies C, Colom-Cadena M, Anton-Fernandez A, King D, Oren I, Rose J, McKenzie CA, Allison E, Smith C, Hardt O, Henstridge CM, Hardingham GE, Spires-Jones TL. Pickett EK, et al. Among authors: henstridge cm. Cell Rep. 2019 Dec 10;29(11):3592-3604.e5. doi: 10.1016/j.celrep.2019.11.044. Cell Rep. 2019. PMID: 31825838 Free PMC article.
Comparative profiling of the synaptic proteome from Alzheimer's disease patients with focus on the APOE genotype.
Hesse R, Hurtado ML, Jackson RJ, Eaton SL, Herrmann AG, Colom-Cadena M, Tzioras M, King D, Rose J, Tulloch J, McKenzie CA, Smith C, Henstridge CM, Lamont D, Wishart TM, Spires-Jones TL. Hesse R, et al. Among authors: henstridge cm. Acta Neuropathol Commun. 2019 Dec 20;7(1):214. doi: 10.1186/s40478-019-0847-7. Acta Neuropathol Commun. 2019. PMID: 31862015 Free PMC article.
Synaptic resilience is associated with maintained cognition during ageing.
King D, Holt K, Toombs J, He X, Dando O, Okely JA, Tzioras M, Rose J, Gunn C, Correia A, Montero C, McAlister H, Tulloch J, Lamont D, Taylor AM, Harris SE, Redmond P, Cox SR, Henstridge CM, Deary IJ, Smith C, Spires-Jones TL. King D, et al. Among authors: henstridge cm. Alzheimers Dement. 2023 Jun;19(6):2560-2574. doi: 10.1002/alz.12894. Epub 2022 Dec 22. Alzheimers Dement. 2023. PMID: 36547260
46 results