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Hypersensitivity to ferroptosis in chromophobe RCC is mediated by a glutathione metabolic dependency and cystine import via solute carrier family 7 member 11.
Zhang L, Hobeika CS, Khabibullin D, Yu D, Filippakis H, Alchoueiry M, Tang Y, Lam HC, Tsvetkov P, Georgiou G, Lamb C, Stone E, Puigserver P, Priolo C, Henske EP. Zhang L, et al. Among authors: henske ep. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2122840119. doi: 10.1073/pnas.2122840119. Epub 2022 Jul 8. Proc Natl Acad Sci U S A. 2022. PMID: 35867762 Free PMC article.
Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion.
Medvetz DA, Khabibullin D, Hariharan V, Ongusaha PP, Goncharova EA, Schlechter T, Darling TN, Hofmann I, Krymskaya VP, Liao JK, Huang H, Henske EP. Medvetz DA, et al. Among authors: henske ep. PLoS One. 2012;7(11):e47842. doi: 10.1371/journal.pone.0047842. Epub 2012 Nov 6. PLoS One. 2012. PMID: 23139756 Free PMC article.
Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide.
Parkhitko AA, Priolo C, Coloff JL, Yun J, Wu JJ, Mizumura K, Xu W, Malinowska IA, Yu J, Kwiatkowski DJ, Locasale JW, Asara JM, Choi AM, Finkel T, Henske EP. Parkhitko AA, et al. Among authors: henske ep. Mol Cancer Res. 2014 Jan;12(1):48-57. doi: 10.1158/1541-7786.MCR-13-0258-T. Epub 2013 Dec 2. Mol Cancer Res. 2014. PMID: 24296756 Free PMC article.
Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells.
Li C, Lee PS, Sun Y, Gu X, Zhang E, Guo Y, Wu CL, Auricchio N, Priolo C, Li J, Csibi A, Parkhitko A, Morrison T, Planaguma A, Kazani S, Israel E, Xu KF, Henske EP, Blenis J, Levy BD, Kwiatkowski D, Yu JJ. Li C, et al. Among authors: henske ep. J Exp Med. 2014 Jan 13;211(1):15-28. doi: 10.1084/jem.20131080. Epub 2014 Jan 6. J Exp Med. 2014. PMID: 24395886 Free PMC article.
Role of BRAFV600E in the first preclinical model of multifocal infiltrating myopericytoma development and microenvironment.
Sadow PM, Priolo C, Nanni S, Karreth FA, Duquette M, Martinelli R, Husain A, Clohessy J, Kutzner H, Mentzel T, Carman CV, Farsetti A, Henske EP, Palescandolo E, Macconaill LE, Chung S, Fadda G, Lombardi CP, De Angelis AM, Durante O, Parker JA, Pontecorvi A, Dvorak HF, Fletcher C, Pandolfi PP, Lawler J, Nucera C. Sadow PM, et al. Among authors: henske ep. J Natl Cancer Inst. 2014 Jul 25;106(8):dju182. doi: 10.1093/jnci/dju182. Print 2014 Aug. J Natl Cancer Inst. 2014. PMID: 25063326 Free PMC article.
213 results