Henry LK - Search Results

1

Post-translational mechanisms in psychostimulant-induced neurotransmitter efflux.

Vaughan RA, Henry LK, Foster JD, Brown CR. Vaughan RA, et al. Among authors: henry lk. Adv Pharmacol. 2024;99:1-33. doi: 10.1016/bs.apha.2023.10.003. Epub 2024 Feb 17. Adv Pharmacol. 2024. PMID: 38467478 Review.

2

Inhibitor mechanisms in the S1 binding site of the dopamine transporter defined by multi-site molecular tethering of photoactive cocaine analogs.

Krout D, Pramod AB, Dahal RA, Tomlinson MJ, Sharma B, Foster JD, Zou MF, Boatang C, Newman AH, Lever JR, Vaughan RA, Henry LK. Krout D, et al. Among authors: henry lk. Biochem Pharmacol. 2017 Oct 15;142:204-215. doi: 10.1016/j.bcp.2017.07.015. Epub 2017 Jul 19. Biochem Pharmacol. 2017. PMID: 28734777 Free PMC article.

3

Computational and biochemical docking of the irreversible cocaine analog RTI 82 directly demonstrates ligand positioning in the dopamine transporter central substrate-binding site.

Dahal RA, Pramod AB, Sharma B, Krout D, Foster JD, Cha JH, Cao J, Newman AH, Lever JR, Vaughan RA, Henry LK. Dahal RA, et al. Among authors: henry lk. J Biol Chem. 2014 Oct 24;289(43):29712-27. doi: 10.1074/jbc.M114.571521. Epub 2014 Aug 31. J Biol Chem. 2014. PMID: 25179220 Free PMC article.

4

Identification of the benztropine analog [¹²⁵I]GA II 34 binding site on the human dopamine transporter.

Tomlinson MJ, Krout D, Pramod AB, Lever JR, Newman AH, Henry LK, Vaughan RA. Tomlinson MJ, et al. Among authors: henry lk. Neurochem Int. 2019 Feb;123:34-45. doi: 10.1016/j.neuint.2018.08.008. Epub 2018 Aug 17. Neurochem Int. 2019. PMID: 30125594 Free PMC article.

5

SLC6 transporters: structure, function, regulation, disease association and therapeutics.

Pramod AB, Foster J, Carvelli L, Henry LK. Pramod AB, et al. Among authors: henry lk. Mol Aspects Med. 2013 Apr-Jun;34(2-3):197-219. doi: 10.1016/j.mam.2012.07.002. Mol Aspects Med. 2013. PMID: 23506866 Free PMC article. Review.

6

Antagonist-induced conformational changes in dopamine transporter extracellular loop two involve residues in a potential salt bridge.

Gaffaney JD, Shetty M, Felts B, Pramod AB, Foster JD, Henry LK, Vaughan RA. Gaffaney JD, et al. Among authors: henry lk. Neurochem Int. 2014 Jul;73:16-26. doi: 10.1016/j.neuint.2013.11.003. Epub 2013 Nov 20. Neurochem Int. 2014. PMID: 24269640 Free PMC article.

7

Novel Azido-Iodo Photoaffinity Ligands for the Human Serotonin Transporter Based on the Selective Serotonin Reuptake Inhibitor (S)-Citalopram.

Kumar V, Yarravarapu N, Lapinsky DJ, Perley D, Felts B, Tomlinson MJ, Vaughan RA, Henry LK, Lever JR, Newman AH. Kumar V, et al. Among authors: henry lk. J Med Chem. 2015 Jul 23;58(14):5609-19. doi: 10.1021/acs.jmedchem.5b00682. Epub 2015 Jul 8. J Med Chem. 2015. PMID: 26153715 Free PMC article.

8

Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.

Henry LK, Field JR, Adkins EM, Parnas ML, Vaughan RA, Zou MF, Newman AH, Blakely RD. Henry LK, et al. J Biol Chem. 2006 Jan 27;281(4):2012-23. doi: 10.1074/jbc.M505055200. Epub 2005 Nov 3. J Biol Chem. 2006. PMID: 16272152 Free article.

9

The external gate of the human and Drosophila serotonin transporters requires a basic/acidic amino acid pair for 3,4-methylenedioxymethamphetamine (MDMA) translocation and the induction of substrate efflux.

Sealover NR, Felts B, Kuntz CP, Jarrard RE, Hockerman GH, Lamb PW, Barker EL, Henry LK. Sealover NR, et al. Among authors: henry lk. Biochem Pharmacol. 2016 Nov 15;120:46-55. doi: 10.1016/j.bcp.2016.09.006. Epub 2016 Sep 13. Biochem Pharmacol. 2016. PMID: 27638414

10

Distinctions between dopamine transporter antagonists could be just around the bend.

Henry LK, Blakely RD. Henry LK, et al. Mol Pharmacol. 2008 Mar;73(3):616-8. doi: 10.1124/mol.107.044586. Epub 2007 Dec 21. Mol Pharmacol. 2008. PMID: 18156312

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