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SAR studies of 4-acyl-1,6-dialkylpiperazin-2-one arenavirus cell entry inhibitors.
Plewe MB, Whitby LR, Naik S, Brown ER, Sokolova NV, Gantla VR, York J, Nunberg JH, Zhang L, Kalveram B, Freiberg AN, Boger DL, Henkel G, McCormack K. Plewe MB, et al. Among authors: henkel g. Bioorg Med Chem Lett. 2019 Nov 15;29(22):126620. doi: 10.1016/j.bmcl.2019.08.024. Epub 2019 Aug 24. Bioorg Med Chem Lett. 2019. PMID: 31537423 Free PMC article.
Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors.
Plewe MB, Sokolova NV, Gantla VR, Brown ER, Naik S, Fetsko A, Lorimer DD, Dranow DM, Smutney H, Bullen J, Sidhu R, Master A, Wang J, Kallel EA, Zhang L, Kalveram B, Freiberg AN, Henkel G, McCormack K. Plewe MB, et al. Among authors: henkel g. ACS Med Chem Lett. 2020 May 1;11(6):1160-1167. doi: 10.1021/acsmedchemlett.0c00025. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32550996 Free PMC article.
Potent inhibition of arenavirus infection by a novel fusion inhibitor.
Gowen BB, Naik S, Westover JB, Brown ER, Gantla VR, Fetsko A, Dagley AL, Blotter DJ, Anderson N, McCormack K, Henkel G. Gowen BB, et al. Among authors: henkel g. Antiviral Res. 2021 Sep;193:105125. doi: 10.1016/j.antiviral.2021.105125. Epub 2021 Jun 29. Antiviral Res. 2021. PMID: 34197863 Free PMC article.
Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1.
Moen SO, Abendroth J, Fairman JW, Baydo RO, Bullen J, Kirkwood JL, Barnes SR, Raymond AC, Begley DW, Henkel G, McCormack K, Tam VC, Phan I, Staker BL, Stacy R, Myler PJ, Lorimer D, Edwards TE. Moen SO, et al. Among authors: henkel g. Sci Rep. 2014 Aug 4;4:5944. doi: 10.1038/srep05944. Sci Rep. 2014. PMID: 25089892 Free PMC article.
Design, synthesis, and evaluation of a novel dual FMS-like tyrosine kinase 3/stem cell factor receptor (FLT3/c-KIT) inhibitor for the treatment of acute myelogenous leukemia.
Davies RJ, Pierce AC, Forster C, Grey R, Xu J, Arnost M, Choquette D, Galullo V, Tian SK, Henkel G, Chen G, Heidary DK, Ma J, Stuver-Moody C, Namchuk M. Davies RJ, et al. Among authors: henkel g. J Med Chem. 2011 Oct 27;54(20):7184-92. doi: 10.1021/jm200712h. Epub 2011 Oct 4. J Med Chem. 2011. PMID: 21970471
109 results