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Colitis ameliorates cholestatic liver disease via suppression of bile acid synthesis.
Gui W, Hole MJ, Molinaro A, Edlund K, Jørgensen KK, Su H, Begher-Tibbe B, Gaßler N, Schneider CV, Muthukumarasamy U, Mohs A, Liao L, Jaeger J, Mertens CJ, Bergheim I, Strowig T, Hengstler JG, Hov JR, Marschall HU, Trautwein C, Schneider KM. Gui W, et al. Among authors: hengstler jg. Nat Commun. 2023 Jun 6;14(1):3304. doi: 10.1038/s41467-023-38840-8. Nat Commun. 2023. PMID: 37280200 Free PMC article.
Long-term hypercaloric diet exacerbates metabolic liver disease in PNPLA3 I148M animals.
Su H, Haque M, Becker S, Edlund K, Duda J, Wang Q, Reißing J, Marschall HU, Candels LS, Mohamed M, Sjöland W, Liao L, Drexler SA, Strowig T, Rahnenführer J, Hengstler JG, Hatting M, Trautwein C. Su H, et al. Among authors: hengstler jg. Liver Int. 2023 Aug;43(8):1699-1713. doi: 10.1111/liv.15587. Epub 2023 Apr 18. Liver Int. 2023. PMID: 37073116
Increased sinusoidal export of drug glucuronides is a compensative mechanism in liver cirrhosis of mice.
Fendt R, Ghallab A, Myllys M, Hofmann U, Hassan R, Hobloss Z, González D, Brackhagen L, Marchan R, Edlund K, Seddek AL, Abdelmageed N, Blank LM, Schlender JF, Holland CH, Hengstler JG, Kuepfer L. Fendt R, et al. Among authors: hengstler jg. Front Pharmacol. 2023 Nov 20;14:1279357. doi: 10.3389/fphar.2023.1279357. eCollection 2023. Front Pharmacol. 2023. PMID: 38053838 Free PMC article.
Microbiota modulation by dietary oat beta-glucan prevents steatotic liver disease progression.
Jaeger JW, Brandt A, Gui W, Yergaliyev T, Hernández-Arriaga A, Muthu MM, Edlund K, Elashy A, Molinaro A, Möckel D, Sarges J, Halibasic E, Trauner M, Kahles F, Rolle-Kampczyk U, Hengstler J, Schneider CV, Lammers T, Marschall HU, von Bergen M, Camarinha-Silva A, Bergheim I, Trautwein C, Schneider KM. Jaeger JW, et al. JHEP Rep. 2024 Jan 3;6(3):100987. doi: 10.1016/j.jhepr.2023.100987. eCollection 2024 Mar. JHEP Rep. 2024. PMID: 38328439 Free PMC article.
High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation.
Seidel F, Cherianidou A, Kappenberg F, Marta M, Dreser N, Blum J, Waldmann T, Blüthgen N, Meisig J, Madjar K, Henry M, Rotshteyn T, Scholtz-Illigens A, Marchan R, Edlund K, Leist M, Rahnenführer J, Sachinidis A, Hengstler JG. Seidel F, et al. Among authors: hengstler jg. Cells. 2022 Oct 27;11(21):3404. doi: 10.3390/cells11213404. Cells. 2022. PMID: 36359802 Free PMC article.
Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth.
Keller M, Rohlf K, Glotzbach A, Leonhardt G, Lüke S, Derksen K, Demirci Ö, Göçener D, AlWahsh M, Lambert J, Lindskog C, Schmidt M, Brenner W, Baumann M, Zent E, Zischinsky ML, Hellwig B, Madjar K, Rahnenführer J, Overbeck N, Reinders J, Cadenas C, Hengstler JG, Edlund K, Marchan R. Keller M, et al. Among authors: hengstler jg. J Exp Clin Cancer Res. 2023 Jan 20;42(1):25. doi: 10.1186/s13046-022-02578-w. J Exp Clin Cancer Res. 2023. PMID: 36670508 Free PMC article.
Sublethal necroptosis signaling promotes inflammation and liver cancer.
Vucur M, Ghallab A, Schneider AT, Adili A, Cheng M, Castoldi M, Singer MT, Büttner V, Keysberg LS, Küsgens L, Kohlhepp M, Görg B, Gallage S, Barragan Avila JE, Unger K, Kordes C, Leblond AL, Albrecht W, Loosen SH, Lohr C, Jördens MS, Babler A, Hayat S, Schumacher D, Koenen MT, Govaere O, Boekschoten MV, Jörs S, Villacorta-Martin C, Mazzaferro V, Llovet JM, Weiskirchen R, Kather JN, Starlinger P, Trauner M, Luedde M, Heij LR, Neumann UP, Keitel V, Bode JG, Schneider RK, Tacke F, Levkau B, Lammers T, Fluegen G, Alexandrov T, Collins AL, Nelson G, Oakley F, Mann DA, Roderburg C, Longerich T, Weber A, Villanueva A, Samson AL, Murphy JM, Kramann R, Geisler F, Costa IG, Hengstler JG, Heikenwalder M, Luedde T. Vucur M, et al. Among authors: hengstler jg. Immunity. 2023 Jul 11;56(7):1578-1595.e8. doi: 10.1016/j.immuni.2023.05.017. Epub 2023 Jun 16. Immunity. 2023. PMID: 37329888 Free article.
Basal MET phosphorylation is an indicator of hepatocyte dysregulation in liver disease.
Burbano de Lara S, Kemmer S, Biermayer I, Feiler S, Vlasov A, D'Alessandro LA, Helm B, Mölders C, Dieter Y, Ghallab A, Hengstler JG, Körner C, Matz-Soja M, Götz C, Damm G, Hoffmann K, Seehofer D, Berg T, Schilling M, Timmer J, Klingmüller U. Burbano de Lara S, et al. Among authors: hengstler jg. Mol Syst Biol. 2024 Mar;20(3):187-216. doi: 10.1038/s44320-023-00007-4. Epub 2024 Jan 12. Mol Syst Biol. 2024. PMID: 38216754 Free PMC article.
531 results