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549 results

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Page 1
Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling.
Schneider KM, Candels LS, Hov JR, Myllys M, Hassan R, Schneider CV, Wahlström A, Mohs A, Zühlke S, Liao L, Elfers C, Kilic K, Henricsson M, Molinaro A, Hatting M, Zaza A, Drasdo D, Frissen M, Devlin AS, Gálvez EJC, Strowig T, Karlsen TH, Hengstler JG, Marschall HU, Ghallab A, Trautwein C. Schneider KM, et al. Among authors: hengstler jg. Nat Metab. 2021 Sep;3(9):1228-1241. doi: 10.1038/s42255-021-00452-1. Epub 2021 Sep 22. Nat Metab. 2021. PMID: 34552267
The ascending pathophysiology of cholestatic liver disease.
Jansen PL, Ghallab A, Vartak N, Reif R, Schaap FG, Hampe J, Hengstler JG. Jansen PL, et al. Among authors: hengstler jg. Hepatology. 2017 Feb;65(2):722-738. doi: 10.1002/hep.28965. Hepatology. 2017. PMID: 27981592 Review.
Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood.
Ghallab A, Hofmann U, Sezgin S, Vartak N, Hassan R, Zaza A, Godoy P, Schneider KM, Guenther G, Ahmed YA, Abbas AA, Keitel V, Kuepfer L, Dooley S, Lammert F, Trautwein C, Spiteller M, Drasdo D, Hofmann AF, Jansen PLM, Hengstler JG, Reif R. Ghallab A, et al. Among authors: hengstler jg. Hepatology. 2019 Feb;69(2):666-683. doi: 10.1002/hep.30213. Epub 2018 Nov 19. Hepatology. 2019. PMID: 30102412 Free PMC article.
Loss of bile salt export pump aggravates lipopolysaccharide-induced liver injury in mice due to impaired hepatic endotoxin clearance.
Remetic J, Ghallab A, Hobloss Z, Brackhagen L, Hassan R, Myllys M, Radun R, Mlitz V, Zhu C, Baumgartner M, Schrottmaier WC, Mussbacher M, Timelthaler G, Scharnagl H, Stojakovic T, Assinger A, Fuchs CD, Hengstler JG, Trauner M. Remetic J, et al. Among authors: hengstler jg. Hepatology. 2022 May;75(5):1095-1109. doi: 10.1002/hep.32289. Epub 2022 Jan 19. Hepatology. 2022. PMID: 34927748 Free PMC article.
Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury.
Schneider KM, Elfers C, Ghallab A, Schneider CV, Galvez EJC, Mohs A, Gui W, Candels LS, Wirtz TH, Zuehlke S, Spiteller M, Myllys M, Roulet A, Ouzerdine A, Lelouvier B, Kilic K, Liao L, Nier A, Latz E, Bergheim I, Thaiss CA, Hengstler JG, Strowig T, Trautwein C. Schneider KM, et al. Among authors: hengstler jg. Cell Mol Gastroenterol Hepatol. 2021;11(4):909-933. doi: 10.1016/j.jcmgh.2020.11.002. Epub 2020 Nov 12. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33189892 Free PMC article.
Epidermal growth factor signaling protects from cholestatic liver injury and fibrosis.
Svinka J, Pflügler S, Mair M, Marschall HU, Hengstler JG, Stiedl P, Poli V, Casanova E, Timelthaler G, Sibilia M, Eferl R. Svinka J, et al. Among authors: hengstler jg. J Mol Med (Berl). 2017 Jan;95(1):109-117. doi: 10.1007/s00109-016-1462-8. Epub 2016 Aug 27. J Mol Med (Berl). 2017. PMID: 27568040 Free PMC article.
Influence of Liver Fibrosis on Lobular Zonation.
Ghallab A, Myllys M, Holland CH, Zaza A, Murad W, Hassan R, Ahmed YA, Abbas T, Abdelrahim EA, Schneider KM, Matz-Soja M, Reinders J, Gebhardt R, Berres ML, Hatting M, Drasdo D, Saez-Rodriguez J, Trautwein C, Hengstler JG. Ghallab A, et al. Among authors: hengstler jg. Cells. 2019 Dec 2;8(12):1556. doi: 10.3390/cells8121556. Cells. 2019. PMID: 31810365 Free PMC article.
Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity.
Ghallab A, Hassan R, Hofmann U, Friebel A, Hobloss Z, Brackhagen L, Begher-Tibbe B, Myllys M, Reinders J, Overbeck N, Sezgin S, Zühlke S, Seddek AL, Murad W, Brecklinghaus T, Kappenberg F, Rahnenführer J, González D, Goldring C, Copple IM, Marchan R, Longerich T, Vucur M, Luedde T, Urban S, Canbay A, Schreiter T, Trauner M, Akakpo JY, Olyaee M, Curry SC, Sowa JP, Jaeschke H, Hoehme S, Hengstler JG. Ghallab A, et al. Among authors: hengstler jg. J Hepatol. 2022 Jul;77(1):71-83. doi: 10.1016/j.jhep.2022.01.020. Epub 2022 Feb 5. J Hepatol. 2022. PMID: 35131407 Free PMC article.
549 results