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ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance.
O'Sullivan J, Kothari C, Caron MC, Gagné JP, Jin Z, Nonfoux L, Beneyton A, Coulombe Y, Thomas M, Atalay N, Meng XW, Milano L, Jean D, Boisvert FM, Kaufmann SH, Hendzel MJ, Masson JY, Poirier GG. O'Sullivan J, et al. Among authors: hendzel mj. Nucleic Acids Res. 2023 Nov 10;51(20):11056-11079. doi: 10.1093/nar/gkad791. Nucleic Acids Res. 2023. PMID: 37823600 Free PMC article.
Compartmentalization of regulatory proteins in the cell nucleus.
Hendzel MJ, Kruhlak MJ, MacLean NA, Boisvert F, Lever MA, Bazett-Jones DP. Hendzel MJ, et al. J Steroid Biochem Mol Biol. 2001 Jan-Mar;76(1-5):9-21. doi: 10.1016/s0960-0760(00)00153-9. J Steroid Biochem Mol Biol. 2001. PMID: 11384859 Review.
144 results