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CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease.
Duan Y, Chu H, Brandl K, Jiang L, Zeng S, Meshgin N, Papachristoforou E, Argemi J, Mendes BG, Wang Y, Su H, Sun W, Llorente C, Hendrikx T, Liu X, Hosseini M, Kisseleva T, Brenner DA, Bataller R, Ramachandran P, Karin M, Fu W, Schnabl B. Duan Y, et al. Among authors: hendrikx t. Nat Commun. 2021 Dec 9;12(1):7172. doi: 10.1038/s41467-021-27385-3. Nat Commun. 2021. PMID: 34887405 Free PMC article.
Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr-/- Mice.
Jeurissen ML, Walenbergh SM, Houben T, Hendrikx T, Li J, Oligschlaeger Y, van Gorp PJ, Gijbels MJ, Bitorina A, Nessel I, Radtke F, Vooijs M, Theys J, Shiri-Sverdlov R. Jeurissen ML, et al. Among authors: hendrikx t. PLoS One. 2016 Nov 29;11(11):e0167199. doi: 10.1371/journal.pone.0167199. eCollection 2016. PLoS One. 2016. PMID: 27898698 Free PMC article.
APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans.
Tsiantoulas D, Eslami M, Obermayer G, Clement M, Smeets D, Mayer FJ, Kiss MG, Enders L, Weißer J, Göderle L, Lambert J, Frommlet F, Mueller A, Hendrikx T, Ozsvar-Kozma M, Porsch F, Willen L, Afonyushkin T, Murphy JE, Fogelstrand P, Donzé O, Pasterkamp G, Hoke M, Kubicek S, Jørgensen HF, Danchin N, Simon T, Scharnagl H, März W, Borén J, Hess H, Mallat Z, Schneider P, Binder CJ. Tsiantoulas D, et al. Among authors: hendrikx t. Nature. 2021 Sep;597(7874):92-96. doi: 10.1038/s41586-021-03818-3. Epub 2021 Aug 25. Nature. 2021. PMID: 34433968
Tetrahydroxylated bile acids improve cholestatic liver and bile duct injury in the Mdr2-/- mouse model of sclerosing cholangitis via immunomodulatory effects.
Fuchs CD, Dixon ED, Hendrikx T, Mlitz V, Wahlström A, Ståhlman M, Scharnagl H, Stojakovic T, Binder CJ, Marschall HU, Trauner M. Fuchs CD, et al. Among authors: hendrikx t. Hepatol Commun. 2022 Sep;6(9):2368-2378. doi: 10.1002/hep4.1998. Epub 2022 Jun 12. Hepatol Commun. 2022. PMID: 35691019 Free PMC article.
Soluble TREM2 levels reflect the recruitment and expansion of TREM2+ macrophages that localize to fibrotic areas and limit NASH.
Hendrikx T, Porsch F, Kiss MG, Rajcic D, Papac-Miličević N, Hoebinger C, Goederle L, Hladik A, Shaw LE, Horstmann H, Knapp S, Derdak S, Bilban M, Heintz L, Krawczyk M, Paternostro R, Trauner M, Farlik M, Wolf D, Binder CJ. Hendrikx T, et al. J Hepatol. 2022 Nov;77(5):1373-1385. doi: 10.1016/j.jhep.2022.06.004. Epub 2022 Jun 21. J Hepatol. 2022. PMID: 35750138 Free article.
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