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DON shares a similar mode of action as the ribotoxic stress inducer anisomycin while TBTO shares ER stress patterns with the ER stress inducer thapsigargin based on comparative gene expression profiling in Jurkat T cells.
Schmeits PC, Katika MR, Peijnenburg AA, van Loveren H, Hendriksen PJ. Schmeits PC, et al. Among authors: hendriksen pj. Toxicol Lett. 2014 Jan 30;224(3):395-406. doi: 10.1016/j.toxlet.2013.11.005. Epub 2013 Nov 15. Toxicol Lett. 2014. PMID: 24247028
Transcriptome-based functional classifiers for direct immunotoxicity.
Shao J, Berger LF, Hendriksen PJ, Peijnenburg AA, van Loveren H, Volger OL. Shao J, et al. Among authors: hendriksen pj. Arch Toxicol. 2014 Mar;88(3):673-89. doi: 10.1007/s00204-013-1179-1. Epub 2013 Dec 20. Arch Toxicol. 2014. PMID: 24356939
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