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Page 1
Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis.
Filliol A, Saito Y, Nair A, Dapito DH, Yu LX, Ravichandra A, Bhattacharjee S, Affo S, Fujiwara N, Su H, Sun Q, Savage TM, Wilson-Kanamori JR, Caviglia JM, Chin L, Chen D, Wang X, Caruso S, Kang JK, Amin AD, Wallace S, Dobie R, Yin D, Rodriguez-Fiallos OM, Yin C, Mehal A, Izar B, Friedman RA, Wells RG, Pajvani UB, Hoshida Y, Remotti HE, Arpaia N, Zucman-Rossi J, Karin M, Henderson NC, Tabas I, Schwabe RF. Filliol A, et al. Among authors: henderson nc. Nature. 2022 Oct;610(7931):356-365. doi: 10.1038/s41586-022-05289-6. Epub 2022 Oct 5. Nature. 2022. PMID: 36198802 Free PMC article.
Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.
Henderson NC, Arnold TD, Katamura Y, Giacomini MM, Rodriguez JD, McCarty JH, Pellicoro A, Raschperger E, Betsholtz C, Ruminski PG, Griggs DW, Prinsen MJ, Maher JJ, Iredale JP, Lacy-Hulbert A, Adams RH, Sheppard D. Henderson NC, et al. Nat Med. 2013 Dec;19(12):1617-24. doi: 10.1038/nm.3282. Epub 2013 Nov 10. Nat Med. 2013. PMID: 24216753 Free PMC article.
αv integrins on mesenchymal cells regulate skeletal and cardiac muscle fibrosis.
Murray IR, Gonzalez ZN, Baily J, Dobie R, Wallace RJ, Mackinnon AC, Smith JR, Greenhalgh SN, Thompson AI, Conroy KP, Griggs DW, Ruminski PG, Gray GA, Singh M, Campbell MA, Kendall TJ, Dai J, Li Y, Iredale JP, Simpson H, Huard J, Péault B, Henderson NC. Murray IR, et al. Among authors: henderson nc. Nat Commun. 2017 Oct 24;8(1):1118. doi: 10.1038/s41467-017-01097-z. Nat Commun. 2017. PMID: 29061963 Free PMC article.
11Beta-hydroxysteroid dehydrogenase-1 deficiency or inhibition enhances hepatic myofibroblast activation in murine liver fibrosis.
Zou X, Ramachandran P, Kendall TJ, Pellicoro A, Dora E, Aucott RL, Manwani K, Man TY, Chapman KE, Henderson NC, Forbes SJ, Webster SP, Iredale JP, Walker BR, Michailidou Z. Zou X, et al. Among authors: henderson nc. Hepatology. 2018 Jun;67(6):2167-2181. doi: 10.1002/hep.29734. Epub 2018 Feb 22. Hepatology. 2018. PMID: 29251794 Free PMC article.
Resolving the fibrotic niche of human liver cirrhosis at single-cell level.
Ramachandran P, Dobie R, Wilson-Kanamori JR, Dora EF, Henderson BEP, Luu NT, Portman JR, Matchett KP, Brice M, Marwick JA, Taylor RS, Efremova M, Vento-Tormo R, Carragher NO, Kendall TJ, Fallowfield JA, Harrison EM, Mole DJ, Wigmore SJ, Newsome PN, Weston CJ, Iredale JP, Tacke F, Pollard JW, Ponting CP, Marioni JC, Teichmann SA, Henderson NC. Ramachandran P, et al. Among authors: henderson nc, henderson bep. Nature. 2019 Nov;575(7783):512-518. doi: 10.1038/s41586-019-1631-3. Epub 2019 Oct 9. Nature. 2019. PMID: 31597160 Free PMC article.
Unravelling fibrosis using single-cell transcriptomics.
Dobie R, Henderson NC. Dobie R, et al. Among authors: henderson nc. Curr Opin Pharmacol. 2019 Dec;49:71-75. doi: 10.1016/j.coph.2019.09.004. Epub 2019 Oct 25. Curr Opin Pharmacol. 2019. PMID: 31670054 Free article. Review.
148 results