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The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver.
Mederacke I, Filliol A, Affo S, Nair A, Hernandez C, Sun Q, Hamberger F, Brundu F, Chen Y, Ravichandra A, Huebener P, Anke H, Shi H, Martínez García de la Torre RA, Smith JR, Henderson NC, Vondran FWR, Rothlin CV, Baehre H, Tabas I, Sancho-Bru P, Schwabe RF. Mederacke I, et al. Among authors: henderson nc. Sci Transl Med. 2022 Apr 6;14(639):eabe5795. doi: 10.1126/scitranslmed.abe5795. Epub 2022 Apr 6. Sci Transl Med. 2022. PMID: 35385339 Free PMC article.
Hepatic fibrogenesis: from within and outwith.
Henderson NC, Forbes SJ. Henderson NC, et al. Toxicology. 2008 Dec 30;254(3):130-5. doi: 10.1016/j.tox.2008.08.017. Epub 2008 Sep 7. Toxicology. 2008. PMID: 18824072 Review.
Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis.
Dobie R, Wilson-Kanamori JR, Henderson BEP, Smith JR, Matchett KP, Portman JR, Wallenborg K, Picelli S, Zagorska A, Pendem SV, Hudson TE, Wu MM, Budas GR, Breckenridge DG, Harrison EM, Mole DJ, Wigmore SJ, Ramachandran P, Ponting CP, Teichmann SA, Marioni JC, Henderson NC. Dobie R, et al. Among authors: henderson nc, henderson bep. Cell Rep. 2019 Nov 12;29(7):1832-1847.e8. doi: 10.1016/j.celrep.2019.10.024. Cell Rep. 2019. PMID: 31722201 Free PMC article.
Liver zonation, revisited.
Paris J, Henderson NC. Paris J, et al. Among authors: henderson nc. Hepatology. 2022 Oct;76(4):1219-1230. doi: 10.1002/hep.32408. Epub 2022 Mar 6. Hepatology. 2022. PMID: 35175659 Free PMC article. Review.
148 results