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Improving target assessment in biomedical research: the GOT-IT recommendations.
Emmerich CH, Gamboa LM, Hofmann MCJ, Bonin-Andresen M, Arbach O, Schendel P, Gerlach B, Hempel K, Bespalov A, Dirnagl U, Parnham MJ. Emmerich CH, et al. Among authors: hempel k. Nat Rev Drug Discov. 2021 Jan;20(1):64-81. doi: 10.1038/s41573-020-0087-3. Epub 2020 Nov 16. Nat Rev Drug Discov. 2021. PMID: 33199880 Free PMC article. Review.
Variability of non-clinical behavioral CNS safety assessment: An intercompany comparison.
Himmel HM; Irwin/FOB Consortium Members; Delaunois A, Deurinck M, Dinklo T, Eriksson Faelker TM, Habermann C, Heers C, Hempel K, Lorenz H, Rosch A, Schauerte H, Teuns G, Traebert M, van Amsterdam C, van der Linde H. Himmel HM, et al. Among authors: hempel k. J Pharmacol Toxicol Methods. 2019 Sep-Oct;99:106571. doi: 10.1016/j.vascn.2019.03.002. Epub 2019 Mar 27. J Pharmacol Toxicol Methods. 2019. PMID: 30928509
Measuring drug absorption improves interpretation of behavioral responses in a larval zebrafish locomotor assay for predicting seizure liability.
Cassar S, Breidenbach L, Olson A, Huang X, Britton H, Woody C, Sancheti P, Stolarik D, Wicke K, Hempel K, LeRoy B. Cassar S, et al. Among authors: hempel k. J Pharmacol Toxicol Methods. 2017 Nov;88(Pt 1):56-63. doi: 10.1016/j.vascn.2017.07.002. Epub 2017 Jul 13. J Pharmacol Toxicol Methods. 2017. PMID: 28712933
Toxicological properties of metaflumizone.
Hempel K, Hess FG, Bögi C, Fabian E, Hellwig J, Fegert I. Hempel K, et al. Vet Parasitol. 2007 Dec 15;150(3):190-5. doi: 10.1016/j.vetpar.2007.08.033. Epub 2007 Oct 22. Vet Parasitol. 2007. PMID: 17933467
242 results