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A reversible state of hypometabolism in a human cellular model of sporadic Parkinson's disease.
Nat Commun. 2023 Nov 23;14(1):7674. doi: 10.1038/s41467-023-42862-7.
Nat Commun. 2023.
PMID: 37996418
Free PMC article.
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.
Schmidt S, Luecken MD, Trümbach D, Hembach S, Niedermeier KM, Wenck N, Pflügler K, Stautner C, Böttcher A, Lickert H, Ramirez-Suastegui C, Ahmad R, Ziller MJ, Fitzgerald JC, Ruf V, van de Berg WDJ, Jonker AJ, Gasser T, Winner B, Winkler J, Vogt Weisenhorn DM, Giesert F, Theis FJ, Wurst W.
Schmidt S, et al. Among authors: hembach s.
Nat Commun. 2022 Aug 16;13(1):4819. doi: 10.1038/s41467-022-32229-9.
Nat Commun. 2022.
PMID: 35974013
Free PMC article.
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Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons.
Giehrl-Schwab J, Giesert F, Rauser B, Lao CL, Hembach S, Lefort S, Ibarra IL, Koupourtidou C, Luecken MD, Truong DJ, Fischer-Sternjak J, Masserdotti G, Prakash N, Ninkovic J, Hölter SM, Vogt Weisenhorn DM, Theis FJ, Götz M, Wurst W.
Giehrl-Schwab J, et al. Among authors: hembach s.
EMBO Mol Med. 2022 May 9;14(5):e14797. doi: 10.15252/emmm.202114797. Epub 2022 Apr 4.
EMBO Mol Med. 2022.
PMID: 35373464
Free PMC article.
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Engrailed 1 deficiency induces changes in ciliogenesis during human neuronal differentiation.
Hembach S, Schmidt S, Orschmann T, Burtscher I, Lickert H, Giesert F, Weisenhorn DV, Wurst W.
Hembach S, et al.
Neurobiol Dis. 2024 May;194:106474. doi: 10.1016/j.nbd.2024.106474. Epub 2024 Mar 20.
Neurobiol Dis. 2024.
PMID: 38518837
Free article.
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Large-scale genetic analysis reveals mammalian mtDNA heteroplasmy dynamics and variance increase through lifetimes and generations.
Burgstaller JP, Kolbe T, Havlicek V, Hembach S, Poulton J, Piálek J, Steinborn R, Rülicke T, Brem G, Jones NS, Johnston IG.
Burgstaller JP, et al. Among authors: hembach s.
Nat Commun. 2018 Jun 27;9(1):2488. doi: 10.1038/s41467-018-04797-2.
Nat Commun. 2018.
PMID: 29950599
Free PMC article.
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Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine.
Ahrens TD, Timme S, Hoeppner J, Ostendorp J, Hembach S, Follo M, Hopt UT, Werner M, Busch H, Boerries M, Lassmann S.
Ahrens TD, et al. Among authors: hembach s.
Epigenetics. 2015;10(5):431-45. doi: 10.1080/15592294.2015.1039216.
Epigenetics. 2015.
PMID: 25923331
Free PMC article.
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